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SENP1

SUMO1/sentrin specific peptidase 1

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1.

Gene Name: SUMO1/sentrin specific peptidase 1
Family/Subfamily: Protease , Cysteine C48
Synonyms: SENP1, Sentrin-specific protease 1, SuPr-2
Target Sequences: NM_014554 NP_055369.1 Q9P0U3

Publications (1)

1
MDM2-ARF complex regulates p53 sumoylation. Chen L, Chen J. Oncogene. 2003 22:5348-57. [PubMed:12917636] Related Antibodies: LS-B3387.

☰ Filters
Antibodies (46)
Proteins (2)
ELISA Kits (1)
Cell-Based (1)
Primary (46)
Recombinant (2)
SENP1 (49)
Human (40)
Mouse (19)
Rat (5)
Bat (3)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (1)
Orangutan (3)
Pig (3)
Rabbit (3)
IHC (21)
IHC-P (8)
WB (42)
Flo (2)
ELISA (27)
IF (2)
IP (3)
Peptide-ELISA (2)
rabbit (44)
mouse (2)
Product Group
IHCPlus (3)
IgG (39)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (44)
OTI1D7 (2)
96-Well Microplate (1)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (5)
Carrier-free (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (25)
aa262-289 (7)
aa28-59 (7)
aa560-590 (7)
C-Terminus (4)
aa1-50 (2)
1-80 aa, N-terminal (1)
Asp2 (1)
N-Terminus (1)
aa150-200 (1)
aa221-460 (1)
aa578-590 (1)
No (48)
Yes (1)
Adherent Cell Cultures (1)
6His, N-terminus (1)
GST, N-terminus (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
Purified (1)
SENP1 Antibody - Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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SENP1 Rabbit anti-Human Polyclonal (aa28-59) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
SENP1 Antibody - Western blot of SENP1 antibody
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SENP1 Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SENP1 Antibody - 1:100 staining human Testis tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SENP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SENP1 Antibody - Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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SENP1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
SENP1 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using SENP1 Antibody at dilution of 1:100
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SENP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
SENP1 Antibody - Western blot of hSENP1-K578 in HL-60, HeLa cell line lysates (35 ug/lane). SENP1 (arrow) was detected using the purified antibody.
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SENP1 Rabbit anti-Human Polyclonal (aa560-590) Antibody
Human
WB
Unconjugated
400 µl/$393
SENP1 Antibody - Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SENP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SENP1 Antibody - Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SENP1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SENP1 Antibody - Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SENP1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SENP1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using SENP1 Polyclonal Antibody at dilution of 1:25.
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SENP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SENP1 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using SENP1 Polyclonal Antibody at dilution of 1:40.
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SENP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
SENP1 Rabbit anti-Human Polyclonal (aa28-59) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SENP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
Select
SENP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
SENP1 Antibody - IHC of SENP1 (D2) pAb in paraffin-embedded human breast carcinoma tissue.
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SENP1 Rabbit anti-Human Polyclonal (Asp2) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
SENP1 Antibody - Immunohistochemical analysis of SENP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SENP1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Dog, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
SENP1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP1.
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SENP1 Mouse anti-Human Monoclonal (OTI1D7) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
SENP1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP1.
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SENP1 Mouse anti-Human Monoclonal (aa221-460) (Carrier-free) (OTI1D7) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
Select
SENP1 Rabbit anti-Mouse Polyclonal (aa262-289) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
Select
SENP1 Rabbit anti-Human Polyclonal (aa560-590) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Viewing 1-25 of 49 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).