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Catalog Number Size Price
LS-C43270-100 100 Tests $456 
Antibody

Monoclonal Mouse anti‑Human SELL / L‑Selectin / CD62L Antibody (clone FMC46, RPE) LS‑C43270

Monoclonal Mouse anti‑Human SELL / L‑Selectin / CD62L Antibody (clone FMC46, RPE) LS‑C43270

Note: This antibody replaces LS-C57183, LS-C13944
Antibody:
SELL / L-Selectin / CD62L Mouse anti-Human Monoclonal (RPE) (FMC46) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:
Price
Catalog Number
$456
LS-C43270-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
SELL / L-Selectin / CD62L Mouse anti-Human Monoclonal (RPE) (FMC46) Antibody
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Other formats:

Specifications

Description
CD62L antibody LS-C43270 is an RPE-conjugated mouse monoclonal antibody to human CD62L (SELL / L-Selectin). Validated for Flow.
Target
Human SELL / L-Selectin / CD62L
Synonyms
SELL | CD62L | CD62L antigen | LAM-1 | LAM1 | LECAM1 | LEU8 | Leukocyte adhesion molecule 1 | Lyam-1 | LSEL | gp90-MEL | HLHRc | PLNHR | L-selectin | Leu-8 | Selectin L | LNHR | LYAM1 | Lymph node homing receptor | Lymphocyte adhesion molecule 1 | TQ1 | Pln homing receptor | CD26L
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Clone
FMC46
Conjugations
R. Phycoerythrin. Also available Unconjugated or conjugated with FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
PHA stimulated lymphoblasts.
Specificity
Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naÃ-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Applications
  • Flow Cytometry (1:1)
  • Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SELL / L-Selectin / CD62L
NM_000655

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/19/2021