SCN2B

sodium channel, voltage-gated, type II, beta subunit

Scn2b encodes one type of beta subunit found in voltage-gated sodium channels. These channels, composed of one alpha and one or two different beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. Scn2b protein, comprised of an extracellular N-terminus with an immunoglobulin-like fold and a single transmembrane domain, has been shown in brain tissues to be covalently linked through disulfide bonds to the alpha subunit. Scn2b is considered an auxiliary subunit that modulates cell-surface expression and gating, though its function in heart myocytes may be limited to cell adhesion. Scnb2 null mice display increased susceptibility to seizures. Expression of Scn2b has been shown to be suppressed with exposure to pneumococcal acute otitis media.

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Products

Antibodies (17)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (17)

Recombinant (2)

Target

SCN2B (21)

Reactivity

Human (17)

Mouse (9)

Rat (11)

Dog (1)

Application

IHC (3)

IHC-P (4)

WB (12)

ELISA (10)

IF (1)

Peptide-ELISA (3)

Host

rabbit (16)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (9)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Clone

2G11-C12 (1)

Format

Preservative Free (1)

Unconjugated (17)

Epitope

N-Terminus (2)

40-120 aa, Internal (1)

Internal (1)

aa114-159 (1)

aa55-104 (1)

aa71-120 (1)

Publications

No (21)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ SCN2B Antibody (N-Terminus) LS-B2625

(4.0) Rating

Antibody:

SCN2B Rabbit anti-Rat Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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SCN2B Antibody (N-Terminus) LS-C46962

Antibody:

SCN2B Rabbit anti-Rat Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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IHC-plus™ SCN2B Antibody LS-B15466

(4.0) Rating

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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SCN2B Antibody LS-C676457

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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SCN2B Antibody LS-C805426

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SCN2B Antibody LS-C753059

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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SCN2B Antibody LS-C824630

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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SCN2B Antibody (40-120 aa, Internal) LS-C384739

Antibody:

SCN2B Rabbit anti-Human Polyclonal (40-120 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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SCN2B Antibody (Preservative Free) LS-C818291

Antibody:

SCN2B Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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SCN2B Antibody (aa71-120) LS-C291394

Antibody:

SCN2B Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SCN2B Antibody (aa55-104) LS-C200643

Antibody:

SCN2B Rabbit anti-Human Polyclonal (aa55-104) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

SCN2B Antibody (clone 2G11-C12) LS-C198151

Antibody:

SCN2B Mouse anti-Human Monoclonal (2G11-C12) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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SCN2B Antibody LS-C489127

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

SCN2B Antibody LS-C489128

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

SCN2B Antibody (aa114-159) LS-C313840

Antibody:

SCN2B Rabbit anti-Human Polyclonal (aa114-159) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

SCN2B Antibody (Internal) LS-C352816

Antibody:

SCN2B Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Dog, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

SCN2B Antibody LS-C357070

Antibody:

SCN2B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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Human SCN2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80647

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.1 kDa

Price:

20 µg/$150

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Human SCN2B Protein (Recombinant GST) (Full Length) - LS-G30328

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

49.39 kDa

Price:

10 µg/$479; 25 µg/$670

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SCN2B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100339

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.1 kDa

Price:

100 µg/$494

Select

Human SCN2B Protein (Recombinant His, N-Terminal) - LS-G144075

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24.1 kDa

Price:

50 µg/$419

Viewing 1-21 of 21 product results

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