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| Catalog Number | Size | Price |
|---|---|---|
| LS-C109037-100 | 100 µg (1 mg/ml) | $442 |
1 of 2
2 of 2
Monoclonal Mouse anti‑Rat SCN10A / Nav1.8 Antibody (clone S134‑12, aa1724‑1956, IHC, WB) LS‑C109037
Monoclonal Mouse anti‑Rat SCN10A / Nav1.8 Antibody (clone S134‑12, aa1724‑1956, IHC, WB) LS‑C109037
Antibody:
SCN10A / Nav1.8 Mouse anti-Rat Monoclonal (aa1724-1956) (S134-12) Antibody
Application:
IHC, ICC, WB
Reactivity:
Rat, Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
SCN10A / Nav1.8 Mouse anti-Rat Monoclonal (aa1724-1956) (S134-12) Antibody
Application:
IHC, ICC, WB
Reactivity:
Rat, Human, Mouse
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
Nav1.8 antibody LS-C109037 is an unconjugated mouse monoclonal antibody to Nav1.8 (SCN10A) (aa1724-1956) from rat. It is reactive with human, mouse and rat. Validated for ICC, IHC and WB. Cited in 2 publications.
Target
Rat SCN10A / Nav1.8
Synonyms
SCN10A | HPN3 | Nav1.8 | PN3 | RPN3 | SNS
Host
Mouse
Reactivity
Rat, Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
S134-12
Conjugations
Purification
Protein G purified from tissue culture supernatant
Modifications
Unmodified
Immunogen
Fusion protein amino acids 1724-1956 of rat Nav1.8, accession number Q62968.
Epitope
aa1724-1956
Specificity
Detects ~220 kD protein. No cross reactivity against other Nav channels.
Applications
- IHC
- ICC (0.1 - 1 µg/ml)
- Western blot (1 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Western Blot: Use the lysate in SDS buffer but without boiling, incubating for 20 mins at 37°C instead.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 50% Glycerol
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SCN10A / Nav1.8
LSBio Ratings
SCN10A / Nav1.8 Antibody (aa1724-1956, clone S134-12) for IHC, ICC, WB/Western LS-C109037 has an LSBio Rating of
Publications (4.1)
Learn more about The LSBio Ratings Algorithm
Publications (2)
The functional consequences of sodium channel NaV<sub> 1.8 in human left ventricular hypertrophy. Ahmad S, Tirilomis P, Pabel S, Dybkova N, Hartmann N, Molina CE, Tirilomis T, Kutschka I, Frey N, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S. ESC heart failure. 2019 February;6:154-163.
Detrimental proarrhythmogenic interaction of Ca 2+<sup>/calmodulin-dependent protein kinase II and Na V<sub> 1.8 in heart failure. Philipp Bengel # , Nataliya Dybkova # , Petros Tirilomis # , Shakil Ahmad , Nico Hartmann , Belal A Mohamed , Miriam Celine Krekeler , Wiebke Maurer , Steffen Pabel, Maximilian Trum, Julian Mustroph, Jan Gummert, Hendrik Milting, Stefan Wagner, Senka Ljubojevic-Holzer, Karl Toischer , Lars S Maier, Gerd Hasenfuss , Katrin Streckfuss-Bömeke # , Samuel Sossalla #. Nature communications. 2021 Nov;12:6586.
Customer Reviews (0)
Featured Products
Species:
Rat, Human, Mouse
Applications:
IHC, ICC, Immunofluorescence, Western blot
Species:
Rat, Human, Monkey, Mouse
Applications:
IHC, IHC - Paraffin, ICC, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
