Products
Services
Research Areas
COVID-19
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-C829135-200 200 µg (1 mg/ml) $405 
Antibody

Recombinant Monoclonal Human SARS‑CoV‑2 Spike Glycoprotein Antibody (clone CR3022, aa318‑510) LS‑C829135

Recombinant Monoclonal Human SARS‑CoV‑2 Spike Glycoprotein Antibody (clone CR3022, aa318‑510) LS‑C829135

Antibody:
SARS-CoV-2 Spike Glycoprotein Human Recombinant Monoclonal (aa318-510) (CR3022) Antibody
Application:
ELISA
Reactivity:
Coronavirus SARS-CoV, Coronavirus SARS-CoV-2
Format:
Unconjugated, Unmodified
Price
Catalog Number
$405
LS-C829135-200
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
SARS-CoV-2 Spike Glycoprotein Human Recombinant Monoclonal (aa318-510) (CR3022) Antibody
Application:
ELISA
Reactivity:
Coronavirus SARS-CoV, Coronavirus SARS-CoV-2
Format:
Unconjugated, Unmodified

Specifications

Description
SARS-CoV-2 Spike Glycoprotein antibody LS-C829135 is an unconjugated human recombinant monoclonal antibody to SARS-CoV-2 Spike Glycoprotein (aa318-510) from coronavirus sars-cov and coronavirus sars-cov-2. Validated for ELISA.
Target
SARS-CoV-2 Spike Glycoprotein
Synonyms
SARS-CoV-2 | SARS-Cov2 | COVID-19 | SARS-CoV2 (COVID-19) Spike
Host
Human
Reactivity
Coronavirus SARS-CoV, Coronavirus SARS-CoV-2 (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Recombinant Monoclonal
Clone
CR3022
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Epitope
aa318-510
Specificity
LS-C829135 is a human IgG kappa recombinant form of a human IgG1 monoclonal antibody generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV (B-cell clone CR3022). This antibody binds to amino acids 318-510 in the S1 domain of the SARS-CoV and SARS-CoV-2 (COVID-19) Spike protein, as well as the P462L-substituted S318–510 fragments of the SARS spike protein. The binding epitope is only accessible in the "open" conformation of the spike protein. Detailed information about antibody binding can be found in these publications: (SARS-CoV-2) Tian X et al. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody. Emerg Microbes Infect. 2020 Feb 17;9(1):382-385. PMID: 32065055(SARS-CoV) ter Meulen et al. Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants PLoS Med. 2006 Jul; 3(7): e237 PMID:16796401.An alternate Rabbit IgG kappa recombinant version of this antibody is also available as LS-C829136.
Applications
  • ELISA
Presentation
PBS, 0.02% ProClin™ 300.
Storage
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About SARS-CoV-2 Spike Glycoprotein
LR1719

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 10/27/2020