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Catalog Number Size Price
LS-C357857-25 25 µg (0.5 mg/ml) $323 
LS-C357857-100 100 µg (0.5 mg/ml) $452 
S1PR1 / EDG1 / S1P1 Antibody - EDG1 antibody western blot of human samples

Polyclonal Rabbit anti‑Human S1PR1 / EDG1 / S1P1 Antibody (C‑Terminus, WB) LS‑C357857

Polyclonal Rabbit anti‑Human S1PR1 / EDG1 / S1P1 Antibody (C‑Terminus, WB) LS‑C357857

Antibody:
S1PR1 / EDG1 / S1P1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$323
LS-C357857-25
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
S1PR1 / EDG1 / S1P1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
S1P1 antibody LS-C357857 is an unconjugated rabbit polyclonal antibody to S1P1 (S1PR1 / EDG1) (C-Terminus) from human. It is reactive with human, mouse and rat. Validated for WB.
Target
Human S1PR1 / EDG1 / S1P1
Synonyms
S1PR1 | CD363 | CD363 antigen | CHEDG1 | ECGF1 | EDG-1 | D1S3362 | EDG1 | S1P1 | S1P receptor Edg-1 | S1P receptor 1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
A recombinant protein fragment from the C-Terminus portion of human EDG1.
Epitope
C-Terminus
Specificity
Human S1PR1 / EDG1 / S1P1.
Applications
  • Western blot (4 - 6 µg/ml)
Usage
EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P). Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.
Presentation
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About S1PR1 / EDG1 / S1P1
P21453 NM_001400 NP_001391.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/28/2021