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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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S100A9 / MRP14 Antibody (clone S36‑48) LS‑C96226
MRP14 antibody LS-C96226 is an unconjugated mouse monoclonal antibody to human MRP14 (S100A9). Validated for ELISA and IHC.
Catalog
Size
Price
LS-C96226-100
100 µg
$560
Description
MRP14 antibody LS-C96226 is an unconjugated mouse monoclonal antibody to human MRP14 (S100A9). Validated for ELISA and IHC.
Target
Human S100A9 / MRP14
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Monoclonal [S36-48]
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
S100A9 / MRP14 antibody was raised against cultured human monocytes
Specificity
The antigen is MRP14, the epitope is suspected in the central region of the peptide. Antigen distribution: Isolated cells: The antigen is found in granulocytes and monocytes. It is absent from all other blood cells. In cultured monocytes, maximum MRP14 expression is found after 3 - 4 days. Myeloid leukaemia cells have been found to be positive as well. Tissue sections: MRP14 is found in a distinct subpopulation of inflammatory perivascular infiltrates of the myelo-monocytic lineage. Macrophages synthesise MRP14 increasingly during the early stages of inflammation. A high MRP14 (and low MRP8) expression by macrophages was reported in granulomatous diseases such as tuberculosis and sarcoidis. In non-granulomatous chronic inflammatory diseases like chronic rheumatoid arthritis, MRP8 and MRP14 positive cells consist of different subpopulations. During early inflammation endothelial cells are also positive with MRP8/14 determined by antibody 27E10. Specificity: Human: MRP14, granulocytes, stimulated monocytes and macrophages. Other: The antibody reacts with bovine spleen. It does not react with swine tissues.
Presentation
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
Reconstitution
0.5ml distilled water
Storage
Store at 4°C.
Restrictions
For research use only.
About S100A9 / MRP14
P06702 NM_002965 NP_002956.1

Popular S100A9 / MRP14 Products

Antibody
Species: Mouse
Applications: Western blot, ELISA
Anti-S100A9 / MRP14 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Anti-S100A9 / MRP14 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human
Applications: Flow Cytometry

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Images

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human liver.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Immunohistochemistry

IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.
IHC of MRP14 / S100A9 antibody. Formalin-fixed, paraffin-embedded human spleen.

Requested From: United States
Date Requested: 11/18/2018
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