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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RP49 / CNG1 Antibody (N‑Terminus) LS‑C14502
CNG1 antibody LS-C14502 is an unconjugated rabbit polyclonal antibody to rat CNG1 (RP49). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C14502-100
100 µg
$755

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Product Description

CNG1 antibody LS-C14502 is an unconjugated rabbit polyclonal antibody to rat CNG1 (RP49). Validated for ELISA and WB.

Specifications

Target
Rat RP49 / CNG1
Synonyms
CNGA1, CNG1, CNCG1, CNG channel alpha-1, CNG-1, Interleukin-1 homologue, RCNC1, Rod alpha CNG channel subunit, RCNCa, RCNCalpha, Rod CNGCalpha, CNCalpha1, CNCG, RETalpha, RP49
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Immunogen
RP49 / CNG1 antibody was raised against synthetic peptide corresponding to 16aa sequence near N-terminus of rat CNG1 (KLH coupled).
Epitope
N-Terminus
Specificity
Recognizes rat CNG1. No significant sequence homology is detected with other CNGs. Species sequence Homology: mouse: 93%; human, canine, bovine, porcine: 87%; chicken: 56%.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml (ECL). ELISA: 0.5-1 ug/ml.
Presentation
100 mM Tris, pH 7.5, 0.05% Sodium Azide, 40% Glycerol, 0.2% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About RP49 / CNG1
Cnga1 is the alpha 1 subunit of cyclic nucleotide-gated (CNG) cation channels involved in visual and olfactory signal transduction. CNGalpha1-3 are able to form functional homooligomeric channels which control the flow of Na+ and Ca2+ into the outer segment of photoreceptor cells in response to light-induced changes in cGMP concentrations. The retinal rod cGMP-gated cation channel is a hetero-oligomer composed of the alpha subunit Cnga1 and a beta subunit. P29973 NM_000087 NP_000078.2


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Requested From: United States
Date Requested: 10/23/2018

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