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RGMB

repulsive guidance molecule family member b

Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.

Gene Name: repulsive guidance molecule family member b
Synonyms: RGMB, DRAGON, Repulsive guidance molecule B, RGM domain family member B, RGM domain family, member B
Target Sequences: Q6NW40 Q6NW40

Publications (2)

1
RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival. Rostislav Novak, Yamen Abu Ahmad, Michael Timaner, Eliya Bitman-Lotan, Avital Oknin-Vaisman, Roi Horwitz, Oliver Hartmann, Michaela Reissland, Viktoria Buck, Mathias Rosenfeldt, David Nikomarov, Markus Elmar Diefenbacher, Yuval Shaked, Amir Orian. Cell death & disease. 2022 September;13:820. [Full Text Article] [PubMed:36153321] [PMC:PMC9509360] Related Antibodies: LS-C185861.
2
Human sensory neurons modulate melanocytes through secretion of RGMB. Siu Yu A Chow, Kazuki Nakayama, Tatsuya Osaki, Maki Sugiyama, Maiko Yamada, Hirotaka Takeuchi, Yoshiho Ikeuchi. Cell reports. 2022 September;40:111366. [Full Text Article] [PubMed:36130522]

☰ Filters
Antibodies (19)
ELISA Kits (1)
Primary (19)
Sandwich (1)
RGMB (20)
Human (20)
Mouse (5)
Rat (3)
Monkey (1)
IHC (2)
IHC-P (1)
WB (19)
ELISA (9)
Peptide-ELISA (1)
rabbit (18)
sheep (1)
Ig (1)
IgG (10)
polyclonal pc (19)
96-Well Microplate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
aa380-407 (7)
C-Terminus (4)
Internal (1)
aa178-437 (1)
No (18)
Yes (2)
Cell Culture Supernatants (1)
Plasma (1)
Serum (1)
RGMB Antibody - IHC of paraffin-embedded U87 xenograft using RGMB antibody at 1:100 dilution.
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RGMB Rabbit anti-Human Polyclonal (aa178-437) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
RGMB ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.21 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
RGMB Antibody - RGMB antibody Western blot of HCT15 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGMB Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
RGMB Antibody - RGMB antibody Western blot of HCT15 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGMB Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
RGMB Antibody - RGMB antibody Western blot of HCT15 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGMB Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
RGMB Antibody - RGMB antibody Western blot of HCT15 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RGMB Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
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RGMB Sheep anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$930
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RGMB Rabbit anti-Human Polyclonal (aa380-407) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RGMB Rabbit anti-Human Polyclonal (aa380-407) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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RGMB Rabbit anti-Human Polyclonal (aa380-407) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RGMB Rabbit anti-Human Polyclonal (aa380-407) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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RGMB Rabbit anti-Human Polyclonal (aa380-407) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RGMB Rabbit anti-Human Polyclonal (aa380-407) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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RGMB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
RGMB Antibody - All lanes: Anti-RGMB Antibody at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: Human brain lysate Lane 3: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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RGMB Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
RGMB Antibody - Western blot analysis of RGMB using COLO205 whole cells lysates
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RGMB Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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RGMB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
RGMB Antibody - RGMB Antibody western blot of Ramos cell line lysates (35 ug/lane). The RGMB antibody detected the RGMB protein (arrow).
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RGMB Rabbit anti-Human Polyclonal (aa380-407) Antibody
Human
WB
Unconjugated
400 µl/$393
RGMB Antibody - Western blot analysis of RGMB expression in HEK293T (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
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RGMB Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
RGMB Antibody - Western blot analysis of extracts of various cell lines, using RGMB antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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RGMB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-20 of 20 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).