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RBBP8 / CTIP Antibody (HRP) LS-C501639

Antibody

RBBP8 / CTIP Antibody (HRP) LS-C501639

Antibody:
Rabbit Polyclonal to Human RBBP8 / CTIP
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:
Price
Catalog Number
$285 
LS-C501639-50
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human RBBP8 / CTIP
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:

Specifications

Description
CTIP antibody LS-C501639 is an HRP-conjugated rabbit polyclonal antibody to human CTIP (RBBP8). Validated for ELISA.

Target
Human RBBP8 / CTIP
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with FITC, Biotin.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
RBBP8 / CTIP antibody was raised against recombinant human DNA endonuclease RBBP8 protein (126-331AA)
Specificity
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About RBBP8 / CTIP
Q99708 NM_002894 NP_002885.1

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