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RBBP8 / CTIP

retinoblastoma binding protein 8

Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in processing meiotic and mitotic double-strand breaks (DSBs) by ensuring both resection and intrachromosomal association of the broken ends. Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA. Component of the BRCA1-RBBP8 complex that regulates CHEK1 activation and controls cell cycle G2/M checkpoints on DNA damage. Promotes microhomology-mediated alternative end joining (A-NHEJ) during class-switch recombination and plays an essential role in chromosomal translocations.

Gene Name: retinoblastoma binding protein 8
Synonyms: RBBP8, CTIP, DNA endonuclease RBBP8, RIM, SAE2, COM1, CtBP-interacting protein, JWDS, RBBP-8, SCKL2, Seckel syndrome 2
Target Sequences: NM_002894 NP_002885.1 Q99708

☰ Filters
Antibodies (42)
Proteins (1)
Primary (42)
Recombinant (1)
RBBP8 / CTIP (43)
Human (42)
Mouse (15)
Rat (5)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Monkey (5)
Orangutan (3)
Rabbit (3)
IHC (12)
IHC-P (5)
WB (29)
ELISA (18)
IF (1)
IP (2)
Peptide-ELISA (4)
rabbit (41)
mouse (1)
Product Group
IHCPlus (2)
IgG (30)
monoclonal mc (1)
polyclonal pc (41)
19E8 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (28)
aa763-792 (7)
aa686-735 (4)
aa791-840 (4)
pSer327 (3)
270-350 aa (1)
600-680 aa (1)
Ab-664 (1)
Internal (1)
aa293-342 (1)
aa525-575 (1)
aa630-679 (1)
aa850-C-term (1)
pSer326 (1)
pThr847 (1)
No (43)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
RBBP8 / CTIP Antibody - Anti-RBBP8 / CTIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
RBBP8 / CTIP Antibody - RBBP8 / CTIP antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa791-840) Antibody
Human
WB
Unconjugated
100 µl/$424
RBBP8 / CTIP Antibody - Anti-RBBP8 / CTIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
RBBP8 / CTIP Protein - 12.5% SDS-PAGE of human RBBP8 stained with Coomassie Blue
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Wheat Germ Extract
GST
128.3 kDa
2 µg/$439
RBBP8 / CTIP Antibody - Immunohistochemical analysis of CTIP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (600-680 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (270-350 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RBBP8 / CTIP Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CTIP Antibody. The picture on the right is blocked with the synthesized peptide.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa293-342) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
RBBP8 / CTIP Antibody - Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using RBBP8 Antibody. The picture on the right is blocked with the synthesized peptide.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa630-679) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
RBBP8 / CTIP Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using CTIP antibody.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
RBBP8 / CTIP Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using RBBP8 antibody.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (Ab-664) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
RBBP8 / CTIP Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer tissue using RBBP8 Antibody at dilution of 1:100
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
RBBP8 / CTIP Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using RBBP8 Polyclonal Antibody at dilution of 1:65.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
RBBP8 / CTIP Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using RBBP8 Polyclonal Antibody at dilution of 1:45.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa763-792) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
RBBP8 / CTIP Antibody - Detection of Mouse CtIP by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-CtIP antibody used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal (aa850-C-term) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
RBBP8 / CTIP Antibody - Western blot analysis of extracts of mouse brain tissue sample using CTIP antibody.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RBBP8 / CTIP Antibody - Western blot analysis of extracts of mouse brain tissue sample using RBBP8 antibody.
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RBBP8 / CTIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
RBBP8 / CTIP Mouse anti-Human Monoclonal (19E8) Antibody
Human
WB
Unconjugated
100 µl/$450
Viewing 1-25 of 43 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).