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Catalog Number Size Price
LS-C510-100 100 µg (0.5 mg/ml) $376 
RB1 / Retinoblastoma / RB Antibody - Immunohistochemistry of DRb-p70 using antibody in sections of primary human breast tumors.
RB1 / Retinoblastoma / RB Antibody - Western blot analysis: HL60 cells were treated with camptothecin for 24 hours.
RB1 / Retinoblastoma / RB Antibody - Immunohistochemistry of DRb-p70 using antibody in sections of primary human breast tumors.
RB1 / Retinoblastoma / RB Antibody - Western blot analysis: HL60 cells were treated with camptothecin for 24 hours.
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Monoclonal Mouse anti‑Human RB1 / Retinoblastoma / RB Antibody (clone 172C1094, IHC, WB) LS‑C510

Monoclonal Mouse anti‑Human RB1 / Retinoblastoma / RB Antibody (clone 172C1094, IHC, WB) LS‑C510

Antibody:
RB1 / Retinoblastoma / RB Mouse anti-Human Monoclonal (172C1094) Antibody
Application:
IHC, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$376
LS-C510-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
RB1 / Retinoblastoma / RB Mouse anti-Human Monoclonal (172C1094) Antibody
Application:
IHC, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
RB antibody LS-C510 is an unconjugated mouse monoclonal antibody to RB (RB1 / Retinoblastoma) from human. It is reactive with human and mouse. Validated for IHC and WB.
Target
Human RB1 / Retinoblastoma / RB
Synonyms
RB1 | p105-Rb | Osteosarcoma | PRb | Retinoblastoma | Retinoblastoma 1 | OSRC | RB | Pp110
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
172C1094
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb.
Specificity
recognizes cleaved Rb (DRb-p70). Does not recognize full-length Rb. In camptothecin treated HL60, an ~68 kD band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
Applications
  • IHC
  • Western blot (2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About RB1 / Retinoblastoma / RB
P06400 NM_000321 NP_000312.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/11/2022