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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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RAPGEF5 / GFR Antibody (aa529‑555, PE) LS‑C284979
GFR antibody LS-C284979 is a PE-conjugated rabbit polyclonal antibody to human GFR (RAPGEF5). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C284979-200
200 µl
$680

Popular RAPGEF5 / GFR Products

Anti-RAPGEF5 / GFR antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11458 dilution 1:50.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemistry of paraffin-embedded human spleen tissue using antibody at dilution of 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: IHC, ELISA

Product Description

GFR antibody LS-C284979 is a PE-conjugated rabbit polyclonal antibody to human GFR (RAPGEF5). Validated for ELISA and WB.
About RAPGEF5 / GFR
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]). Q92565 D87467 BAA13406.2

RAPGEF5 Antibody, GFR Antibody, KIAA0277 Antibody, M-Ras-regulated Rap GEF Antibody, M-Ras-regulated GEF Antibody, MRGEF Antibody, Related to Epac Antibody, REPAC Antibody, MR-GEF Antibody


Specifications

Target
Human RAPGEF5 / GFR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Phycoerythrin. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, HRP.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
  • (applications tested for the base form of this product only)
Epitope
aa529-555
Specificity
This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, No preservatives added
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C for up to 6 months. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/21/2018

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