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RAD9A / RAD9

RAD9 homolog A (S. pombe)

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.

Gene Name: RAD9 homolog A (S. pombe)
Synonyms: RAD9A, HRAD9, RAD9, RAD9 homolog, RAD9 (S. pombe) homolog, RAD9 homolog A (S. pombe)
Target Sequences: NM_004584 NP_004575.1 Q99638

Publications (2)

1
The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling. Xu X, Vaithiyalingam S, Glick GG, Mordes DA, Chazin WJ, Cortez D. Molecular and cellular biology. 2008 28:7345-53. [PubMed:18936170] [PMC:PMC2593429] Related Antibodies: LS-C96952, LS-C96945.
2
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage. Medhurst AL, Warmerdam DO, Akerman I, Verwayen EH, Kanaar R, Smits VA, Lakin ND. Journal of cell science. 2008 121:3933-40. [PubMed:19020305]

☰ Filters
Antibodies (98)
Proteins (4)
Over-Expression Lysate (2)
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Recombinant (2)
RAD9A / RAD9 (102)
Human (95)
Mouse (16)
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rabbit (89)
mouse (8)
goat (1)
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monoclonal mc (8)
polyclonal pc (90)
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aa350-C-term (2)
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RAD9A / RAD9 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer387) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
RAD9A / RAD9 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer272) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
RAD9A / RAD9 Antibody - Immunohistochemistry of paraffin-embedded rat liver tissue.
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RAD9A / RAD9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RAD9A / RAD9 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
RAD9A / RAD9 Antibody
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RAD9A / RAD9 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
RAD9A / RAD9 Antibody - Rad9 antibody detects RAD9A protein at nucleus on HBL435 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HBL435 xenograft. Rad9 antibody dilution:1:500.
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (aa197-421) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
RAD9A / RAD9 Antibody - Rad9 Antibody (S387) immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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RAD9A / RAD9 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) (Biotin) Antibody
Human
ELISA, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
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RAD9A / RAD9 Rabbit anti-Human Polyclonal (Ser387) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
RAD9A / RAD9 Antibody - Western blot of RAD9 using antibody at 2 ug/ml against recombinant RAD9.
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RAD9A / RAD9 Mouse anti-Human Monoclonal (93A535 ) Antibody
Human
ICC, IHC, IP, WB
Unconjugated
0.1 mg/$386
RAD9A / RAD9 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-RAD9A mouse monoclonal antibody. (Dilution 1:50).
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RAD9A / RAD9 Mouse anti-Human Monoclonal (OTI7B11) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
RAD9A / RAD9 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-RAD9A mouse monoclonal antibody. (Dilution 1:50).
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RAD9A / RAD9 Mouse anti-Human Monoclonal (Carrier-free) (OTI7B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
RAD9A / RAD9 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) Antibody
Human
DB, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) Antibody
Human
DB, ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) (HRP) Antibody
Human
DB, ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) (Biotin) Antibody
Human
DB, ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) (FITC) Antibody
Human
DB, ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) (PE) Antibody
Human
DB, ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
RAD9A / RAD9 Rabbit anti-Human Polyclonal (pSer328) (APC) Antibody
Human
DB, ELISA, IHC, WB
APC Conjugated
200 µl/$952
RAD9A / RAD9 Antibody - IHC of paraffin-embedded Ovary tissue using anti-RAD9A mouse monoclonal antibody. (Dilution 1:50).
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RAD9A / RAD9 Mouse anti-Human Monoclonal (OTI5D9) Antibody
Dog, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
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RAD9A / RAD9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-25 of 102 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).