Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

RAD51L3 / RAD51D

RAD51 paralog D

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.

Gene Name: RAD51 paralog D
Synonyms: RAD51D, BROVCA4, HsTRAD, RAD51 homolog D, RAD51-like protein 3, Recombination repair protein, R51H3, RAD51L3, RAD51 (S. cerevisiae)-like 3, RAD51-like 3 (S. cerevisiae), TRAD
Target Sequences: NM_002878 NP_002869.3 O75771

Publications (6)

1
Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression. Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG. Cancer research. 2004 64:8526-33. [PubMed:15574758]
2
Repression of mutagenesis by Rad51D-mediated homologous recombination. Hinz JM, Tebbs RS, Wilson PF, Nham PB, Salazar EP, Nagasawa H, Urbin SS, Bedford JS, Thompson LH. Nucleic acids research. 2006 34:1358-68. [PubMed:16522646] [PMC:PMC1390685]
3
Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination. Wiese C, Hinz JM, Tebbs RS, Nham PB, Urbin SS, Collins DW, Thompson LH, Schild D. Nucleic acids research. 2006 34:2833-43. [PubMed:16717288] [PMC:PMC1464408]
4
Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1. Chattopadhyay R, Das S, Maiti AK, Boldogh I, Xie J, Hazra TK, Kohno K, Mitra S, Bhakat KK. Molecular and cellular biology. 2008 28:7066-80. [PubMed:18809583] [PMC:PMC2593380]
5
Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Blood. 2009 113:2290-7. [PubMed:19050310] [PMC:PMC2652372]
6
DNA repair genes implicated in triple negative familial non-BRCA1/2 breast cancer predisposition. Ollier M, Radosevic-Robin N, Kwiatkowski F, Ponelle F, Viala S, Privat M, Uhrhammer N, Bernard-Gallon D, Penault-Llorca F, Bignon YJ, Bidet Y. American journal of cancer research. 2015 5:2113-26. (ICC, IHC; Human) [PubMed:26328243] [PMC:PMC4548324] Related Antibodies: LS-C177138.
more

☰ Filters
Antibodies (21)
Proteins (8)
Over-Expression Lysate (4)
Primary (21)
Recombinant (4)
RAD51L3 / RAD51D (29)
Human (21)
Mouse (1)
Rat (1)
Chimpanzee (3)
Gibbon (3)
Hamster (1)
Orangutan (3)
IHC (7)
IHC-P (4)
WB (18)
ELISA (5)
ICC (1)
IF (3)
Peptide-ELISA (3)
rabbit (18)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (8)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (19)
1C8-3C12 (1)
5B3/6 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (15)
C-Terminus (4)
aa259-308 (4)
aa1-328 (2)
100-180 aa, Internal (1)
Ala152 (1)
Internal (1)
aa131-180 (1)
aa2-15 (1)
No (28)
Yes (1)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
RAD51L3 / RAD51D Antibody - Rad51D detected in HEK293 lysates using a 1:1000 dilution of Rad51D antibody (purified).
Select
RAD51L3 / RAD51D Mouse anti-Human Monoclonal (5B3/6) Antibody
Human
ICC, IF, WB
Unconjugated
0.1 ml/$386
RAD51L3 / RAD51D Antibody - Western blot of Rad51D (A152) pAb in extracts from Jurkat cells.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (Ala152) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
RAD51L3 / RAD51D Antibody - Immunohistochemical analysis of RAD51D staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
RAD51L3 / RAD51D Antibody - Anti-RAD51L3 / RAD51D antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa131-180) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
RAD51L3 / RAD51D Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer using antibody at 1:100 dilution.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa1-328) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
RAD51L3 / RAD51D Antibody - Immunofluorescence analysis of A549 cells.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (100-180 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RAD51L3 / RAD51D Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer using antibody at 1:100 dilution.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa1-328) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
RAD51L3 / RAD51D Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RAD51L3 / RAD51D Antibody - Detection limit for recombinant GST tagged RAD51L3 is approximately 1 ng/ml as a capture antibody.
Select
RAD51L3 / RAD51D Mouse anti-Human Monoclonal (1C8-3C12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
RAD51L3 / RAD51D Antibody - Western blot analysis of extracts from Jurkat cells, using RAD51L3 antibody.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
RAD51L3 / RAD51D Antibody - RAD51L3 / RAD51D antibody Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
RAD51L3 / RAD51D Antibody - RAD51L3 / RAD51D antibody Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
RAD51L3 / RAD51D Antibody - RAD51L3 / RAD51D antibody Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
RAD51L3 / RAD51D Antibody - RAD51L3 / RAD51D antibody Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
RAD51L3 / RAD51D Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa259-308) Antibody
Human
WB
Unconjugated
100 µl/$424
RAD51L3 / RAD51D Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa259-308) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
RAD51L3 / RAD51D Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa259-308) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
RAD51L3 / RAD51D Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal (aa259-308) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Select
RAD51L3 / RAD51D Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$331
Select
RAD51L3 / RAD51D Goat anti-Human Polyclonal (aa2-15) Antibody
Hamster, Human
Peptide-ELISA
Unconjugated
100 µg/$401
RAD51L3 / RAD51D Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
RAD51L3 / RAD51D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.8 kDa
20 µg/$150
RAD51L3 / RAD51D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
34.9 kDa
20 µg/$150
RAD51L3 / RAD51D Protein - 12.5% SDS-PAGE of human RAD51L3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
61.82 kDa
10 µg/$479; 25 µg/$670
Viewing 1-25 of 29 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).