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RAD1

RAD1 homolog (S. pombe)

Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity.

Gene Name: RAD1 homolog (S. pombe)
Synonyms: RAD1, DNA repair exonuclease REC1, RAD1 (S. pombe) homolog, REC1, RAD1 homolog (S. pombe), Exonuclease homolog RAD1, HRAD1
Target Sequences: NM_002853 NP_002844.1 O60671

☰ Filters
Antibodies (25)
Proteins (9)
Over-Expression Lysate (4)
Primary (25)
Recombinant (5)
RAD1 (34)
Human (25)
Mouse (8)
Rat (4)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (3)
IHC (6)
IHC-P (2)
WB (22)
ELISA (11)
ICC (1)
IF (3)
IP (2)
Peptide-ELISA (1)
RNAi (1)
rabbit (23)
mouse (2)
Product Group
IHCPlus (1)
IgG (15)
IgG3,k (1)
monoclonal mc (2)
polyclonal pc (23)
1G2 (1)
4126 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (17)
aa118-146 (7)
aa179-228 (4)
Internal (1)
N-Terminus (1)
aa1-282 (1)
aa77-282 (1)
No (34)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (5)
Human (7)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (3)
RAD1 Antibody - Anti-RAD1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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RAD1 Mouse anti-Human Monoclonal (N-Terminus) (4126) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
RAD1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human heart tissue using RAD antibody.
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
RAD1 Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RAD1 Antibody - Immunohistochemistry of paraffin-embedded human testicle using antibody at 1:100 dilution.
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RAD1 Rabbit anti-Human Polyclonal (aa1-282) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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RAD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
RAD1 Antibody - Western blot of RAD1 expression in transfected 293T cell line by RAD1 monoclonal antibody (M01), clone 1G2.
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RAD1 Mouse anti-Human Monoclonal (1G2) Antibody
Human
ELISA, RNAi, WB
Unconjugated
100 µg/$423
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RAD1 Antibody - Immunofluorescence staining of RAD1 in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human RAD1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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RAD1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
RAD1 Rabbit anti-Human Polyclonal (aa118-146) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
RAD1 Antibody - Western blot analysis of RAD1 expression in HeLa cells lysate. The lane on the left is treated with the antigen-specific peptide.
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
RAD1 Antibody - RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD1 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human
WB
Unconjugated
100 µl/$424
RAD1 Antibody - RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD1 Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
RAD1 Antibody - RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD1 Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
RAD1 Antibody - RAD1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RAD1 Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Rabbit, Dog, Guinea pig, Bovine, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
RAD1 Antibody - RAD1 Antibody western blot of K562 cell line lysates (35 ug/lane). The RAD1 antibody detected the RAD1 protein (arrow).
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RAD1 Rabbit anti-Human Polyclonal (aa118-146) Antibody
Human
WB
Unconjugated
400 µl/$393
RAD1 Antibody - Western blot analysis of RAD1 expression in A549 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
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RAD1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
Select
RAD1 Rabbit anti-Human Polyclonal (aa77-282) Antibody
Human
Unconjugated
100 µl/$402
Select
RAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Unconjugated
100 µl/$357
Viewing 1-25 of 34 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).