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QPRT
quinolinate phosphoribosyltransferase
QPRT is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
| Gene Name: | quinolinate phosphoribosyltransferase |
| Synonyms: | QPRT, QPRTase, QAPRTase |
| Target Sequences: | NM_014298 NP_055113.2 Q15274 |
Publications (2)
1
Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease. Jones SP, Franco NF, Varney B, Sundaram G, Brown DA, de Bie J, Lim CK, Guillemin GJ, Brew BJ. PloS one. 2015 10:e0131389. (WB; Human)
[Full Text Article]
[PubMed:26114426]
[PMC:PMC4482723]
Related Antibodies: LS-C115527.
2
Berberine-induced TFEB deacetylation by SIRT1 promotes autophagy in peritoneal macrophages. Yinghong Zheng, Jiayuan Kou, Pengyu Wang, Ting Ye, Zitong Wang, Ziyu Gao, Lin Cong, Manman Li, Bowen Dong, Wei Yang, Quanfeng Li, Hong Li, Rui Wang, Liming Yang. Aging. 2021 Feb;13:7096-7119. [Full Text Article]
[PubMed:33639613]
[PMC:PMC7993719]
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QPRT Mouse anti-Human Monoclonal (OTI7A8) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI7A8) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
QPRT Mouse anti-Human Monoclonal (AT24C4) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
QPRT Mouse anti-Human Monoclonal (OTI1C10) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI1C10) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Mouse anti-Human Monoclonal (OTI4E6) Antibody
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4E6) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
![QPRT Antibody - Immunoperoxidase of monoclonal antibody to QPRT on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml].](https://lsbio-7d62.kxcdn.com/image2/qprt-antibody-clone-5d11-ls-c133705/52660_4940709.jpg)
QPRT Mouse anti-Human Monoclonal (5D11) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
QPRT Mouse anti-Human Monoclonal (OTI4E5) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4E5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
QPRT Mouse anti-Human Monoclonal (OTI3B3) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI3B3) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Rabbit anti-Human Polyclonal (aa206-234) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
QPRT Rabbit anti-Human Polyclonal (aa206-234) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
QPRT Rabbit anti-Human Polyclonal (aa206-234) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
QPRT Rabbit anti-Human Polyclonal (aa206-234) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
QPRT Mouse anti-Human Monoclonal (OTI4B3) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4B3) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Mouse anti-Human Monoclonal (OTI4B4) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI4B4) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
QPRT Mouse anti-Human Monoclonal (OTI2H4) Antibody
IF, WB
Unconjugated
100 µl/$434
QPRT Mouse anti-Human Monoclonal (Carrier-free) (OTI2H4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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