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PTPRH / SAP-1
protein tyrosine phosphatase, receptor type, H
May contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associated substrates and thus negatively regulating integrin-promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activation of MAP kinase and surface expression of CD69. Inhibits TCR-induced tyrosine phosphorylation of LAT and ZAP70. Inhibits both basal activity of DOK1 and its CD2-induced tyrosine phosphorylation. Induces dephosphorylation of p130cas, focal adhesion kinase and c-Src. Reduces migratory activity of Jurkat cells.
| Gene Name: | protein tyrosine phosphatase, receptor type, H |
| Family/Subfamily: | Protein Phosphatase , R3 |
| Synonyms: | PTPRH, SAP-1, R-PTP-H, PTP sap-1, SAP1 |
| Target Sequences: | NM_002842 |
☰ Filters
Products
Antibodies
(29)
Proteins
(6)
Type
Over-Expression Lysate
(2)
Primary
(29)
Recombinant
(4)
Target
PTPRH / SAP-1
(35)
Reactivity
Human
(13)
Mouse
(8)
Rat
(8)
Pig
(8)
Application
WB
(28)
Peptide-ELISA
(1)
Host
rabbit
(28)
goat
(1)
Clonality
polyclonal pc
(29)
Format
APC
(3)
APC Conjugated
(3)
Biotin Conjugated
(4)
Cy3 Conjugated
(3)
Cy7 Conjugated
(3)
FITC Conjugated
(4)
HRP Conjugated
(4)
PE Conjugated
(3)
Unconjugated
(5)
Epitope
aa551-802
(8)
aa685-909
(8)
aa844-1096
(8)
aa576-625
(4)
aa807-818
(1)
Publications
No
(35)
Tag
His-T7
(3)
Myc-DDK (Flag)
(3)
Species
Human
(3)
Mouse
(1)
Rat
(1)
Source
293T Cells
(1)
E. coli
(3)
HEK 293 Cells
(2)
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$547; 1 ml/$649; 2 ml/$884; 5 ml/$1,475
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
PTPRH / SAP-1 Rabbit anti-Mouse Polyclonal (aa685-909) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa576-625) Antibody
Human
WB
Unconjugated
100 µl/$424
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa576-625) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa576-625) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa576-625) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) Antibody
Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (HRP) Antibody
Pig, Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$374; 500 µl/$537; 1 ml/$629; 2 ml/$863; 5 ml/$1,429
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (Biotin) Antibody
Pig, Human
WB
Biotin Conjugated
100 µl/$307; 200 µl/$349; 500 µl/$487; 1 ml/$556; 2 ml/$745; 5 ml/$1,209
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (FITC) Antibody
Pig, Human
WB
FITC Conjugated
100 µl/$334; 200 µl/$387; 500 µl/$562; 1 ml/$677; 2 ml/$914; 5 ml/$1,539
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (APC, Cy7) Antibody
Pig, Human
WB
APC, Cy7 Conjugated
100 µl/$475; 200 µl/$587; 500 µl/$1,064; 1 ml/$1,257; 2 ml/$1,759; 5 ml/$3,297
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (Cy3) Antibody
Pig, Human
WB
Cy3 Conjugated
100 µl/$387; 200 µl/$462; 500 µl/$774; 1 ml/$929; 2 ml/$1,189; 5 ml/$2,199
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (PE) Antibody
Pig, Human
WB
PE Conjugated
100 µl/$387; 200 µl/$462; 500 µl/$774; 1 ml/$929; 2 ml/$1,189; 5 ml/$2,199
PTPRH / SAP-1 Rabbit anti-Human Polyclonal (aa844-1096) (APC) Antibody
Pig, Human
WB
APC Conjugated
100 µl/$387; 200 µl/$462; 500 µl/$774; 1 ml/$929; 2 ml/$1,189; 5 ml/$2,199
PTPRH / SAP-1 Goat anti-Human Polyclonal (aa807-818) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$401
PTPRH / SAP-1 Rabbit anti-Rat Polyclonal (aa551-802) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
PTPRH / SAP-1 Rabbit anti-Rat Polyclonal (aa551-802) (HRP) Antibody
Rat
WB
HRP Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557
PTPRH / SAP-1 Rabbit anti-Rat Polyclonal (aa551-802) (Biotin) Antibody
Rat
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
PTPRH / SAP-1 Rabbit anti-Rat Polyclonal (aa551-802) (FITC) Antibody
Rat
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
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of 35
product results
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