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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTPRF Antibody (aa1315‑1607, clone S165‑38, Atto 488) LS‑C229137
PTPRF antibody LS-C229137 is an Atto 488-conjugated mouse monoclonal antibody to PTPRF from human, mouse and rat. Validated for ICC and WB.
Antibody
Catalog
Size
Price
LS-C229137-100
100 µg
Unavailable

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Product Description

PTPRF antibody LS-C229137 is an Atto 488-conjugated mouse monoclonal antibody to PTPRF from human, mouse and rat. Validated for ICC and WB.
About PTPRF
PTPRF is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. P10586 NM_002840 NP_002831.2

PTPRF Antibody, LAR Antibody, LCA-homolog Antibody, Ptp-lar Antibody


Specifications

Target
Human PTPRF
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [S165-38]
Conjugations
Atto 488. Also available Unconjugated or conjugated with Atto 390, Atto 565, Atto 594, Atto 633, Atto 655, Atto 680, Atto 700, AP, APC, Biotin, FITC, PE, Atto 594, PerCP, RPE, SA.
Purification
Protein G purified from tissue culture supernatant
Modifications
Unmodified
Applications
  • ICC
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
PTPRF antibody was raised against fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR (accession # P10586). 97% identical in both rat and mouse. >80% identity with PTPRD and PTPRS. >50% identity with PTPRM and PTPRK.
Epitope
aa1315-1607
Specificity
Detects a 85 kD protein (full length protein is 210 kD - smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/18/2018

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