Target
Human PTGS2 / COX2 / COX-2
Synonyms
PTGS2 | COX-2 | Cyclooxygenase-2 | COX2 | Cyclooxygenase 2b | HCox-2 | GRIPGHS | PGH synthase 2 | PGHS-2 | PHS II | PHS-2 | Prostaglandin H2 synthase 2 | PGG/HS | Prostaglandin G/H synthase 2
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
Synthetic peptide corresponding to aa 580-599 (NASSSRSGLDDINPTVLLKE) of human COX-2. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Sheep, Panda, Dog, Bovine, Pig, Opossum (95%); Platypus (90%); Elephant, Horse (85%).
Specificity
Recognizes human and sheep COX-2. Does not cross-react with mouse, rat, and rabbit COX-2 and COX-1 (all species). Species sequence homology: bovine and canine.