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Prostaglandin D Synthase

prostaglandin D2 synthase 21kDa (brain)

Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Gene Name: prostaglandin D2 synthase 21kDa (brain)
Synonyms: PTGDS, Beta-trace protein, LPGDS, PGD2, PGD2 synthase, PGDS, Prostaglandin D synthase, Prostaglandin-D2 synthase, L-PGDS, PDS, Cerebrin-28, PGDS2, Prostaglandin-H2 D-isomerase
Target Sequences: NM_000954 NP_000945.3 P41222

Publications (1)

1
Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes. Takeda K, Takahashi NH, Yoshizawa M, Shibahara S. Journal of biochemistry. 2010 148:139-48. (WB; Human) [PubMed:20403807]

☰ Filters
Antibodies (59)
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Prostaglandin D Synthase (89)
Human (55)
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Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa1-50) (DY550) Antibody
Human
IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Prostaglandin D Synthase ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Prostaglandin D Synthase Antibody - PTGDS antibody (0.1 ug/ml) staining of Mouse fetal Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Prostaglandin D Synthase Goat anti-Mouse Polyclonal (aa149-162) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa120-190) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa120-190) (Biotin) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Cat, Primate, Human
IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa120-190) (DY650) Antibody
Human
IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
Prostaglandin D Synthase Antibody - Anti-PTGDS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (aa120-190) (DY488) Antibody
Human
IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
Prostaglandin D Synthase Antibody - PTGDS antibody PTGDS(prostaglandin D2 synthase 21kDa (brain)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
Prostaglandin D Synthase Antibody - PTGDS antibody PTGDS(prostaglandin D2 synthase 21kDa (brain)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Rat, Pig, Horse, Orangutan, Gibbon, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
Prostaglandin D Synthase Antibody - Immunohistochemical analysis of PGD2 synthase staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$688
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Prostaglandin D Synthase Sheep anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$628
Prostaglandin D Synthase Antibody - Anti-PTGDS / PGDS antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Prostaglandin D Synthase Goat anti-Human Polyclonal (aa27-38) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Prostaglandin D Synthase Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
Prostaglandin D Synthase ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cerebrospinal Fluid, Plasma, Serum
1 Plate/$764
Prostaglandin D Synthase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Select
Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Prostaglandin D Synthase Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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Prostaglandin D Synthase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 89 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).