Target
Rat PRKCZ / PKC-Zeta
Synonyms
PRKCZ | PKC-ZETA | PKC2 | Pkcz | PKCzeta | Protein kinase c zeta | Protein kinase C zeta type | NPKC-zeta | PKC Zeta | Protein kinase C, zeta | Protein kinase Czeta
Reactivity
Rat, Mouse
(tested or 100% immunogen sequence identity)
Immunogen
KLH-conjugated synthetic peptide from C-Terminus residues 577-592 (C-GFEYINPLLLSAEESV) of rat PKC-zeta with an N-Terminus cysteine. Percent identity by BLAST analysis: Mouse, Rat (100%); Human, Gorilla, Orangutan, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Horse, Rabbit, Stickleback, Pufferfish (94%); Chimpanzee, Gibbon, Hamster, Bat, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Zebrafish (88%); Sea anemone (81%).
Specificity
Recognizes PKC zeta (72kD). Also recognizes a 66kD protein whose detection is blocked with the immunizing peptide and a non-specific protein at ~54kD whose detection is not blocked by the immunizing peptide. Species cross-reactivity: mouse and human.