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PRKAB1 / AMPK Beta 1

protein kinase, AMP-activated, beta 1 non-catalytic subunit

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Gene Name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Family/Subfamily: Protein Kinase Non Catalytic , AMPK/SNF1
Synonyms: PRKAB1, AMPK beta 1, AMPK subunit beta-1, AMPKb, AMPK, AMPK beta -1 chain, HAMPKb
Target Sequences: NM_006253 NP_006244.2 Q9Y478

Publications (1)

1
Association of AMP-activated protein kinase subunits with glycogen particles as revealed in situ by immunoelectron microscopy. Bendayan M, Londono I, Kemp BE, Hardie GD, Ruderman N, Prentki M. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2009 57:963-71. (WB) [PubMed:19581628] [PMC:PMC2746729]

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Antibodies (71)
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PRKAB1 / AMPK Beta 1 (89)
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PRKAB1 / AMPK Beta 1 Antibody - Anti-PRKAB1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (aa147-196) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
PRKAB1 / AMPK Beta 1 Antibody - Immunohistochemical analysis of AMPK beta 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
PRKAB1 / AMPK Beta 1 Antibody - Immunohistochemical analysis of AMPK beta 1 (pS182) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer182) Antibody
Mouse, Bovine, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$315
PRKAB1 / AMPK Beta 1 Antibody - Immunohistochemical analysis of paraffin-embedded Breast cancer using AMPK beta 1 mouse monoclonal antibody (1:200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
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PRKAB1 / AMPK Beta 1 Mouse anti-Human Monoclonal Antibody
Mouse, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$391
PRKAB1 / AMPK Beta 1 Antibody - 1:100 staining human kindey carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer181) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRKAB1 / AMPK Beta 1 Antibody - 1:100 staining rat lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PRKAB1 / AMPK Beta 1 Antibody - Anti-PRKAB1 / AMPK antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (aa4-34) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PRKAB1 / AMPK Beta 1 Antibody - IHC of AMPK1 (H17) pAb in paraffin-embedded human colon carcinoma tissue.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (His17) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PRKAB1 / AMPK Beta 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
PRKAB1 / AMPK Beta 1 Antibody - Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using AMPK beta1 (Phospho-Ser181) Antibody. The picture on the right is blocked with the phospho peptide.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer181) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$489
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (aa4-34) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRKAB1 / AMPK Beta 1 Antibody - Western blot of Phospho-AMPKbeta1 (S182) antibody
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRKAB1 / AMPK Beta 1 Antibody - Western blot of AMPKbeta1 antibody
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (120-200 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PRKAB1 / AMPK Beta 1 Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human skeletal muscletissue using AMPK ß1 (Phospho-Ser181) Antibody.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer181) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PRKAB1 / AMPK Beta 1 Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human skeletal muscle tissue using AMPK ß1 (Ab-181) Antibody.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (p181) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PRKAB1 / AMPK Beta 1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using AMPK ß1 (Ab-181) antibody.
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PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (p181) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PRKAB1 / AMPK Beta 1 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using AMPK ß1 (Phospho-Ser181) antibody.
Select
PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer181) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PRKAB1 / AMPK Beta 1 Antibody - Immunohistochemical analysis of paraffin-embedded Breast cancer using AMPK beta 1 mouse mAb (1:200 dilution).Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
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PRKAB1 / AMPK Beta 1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
Select
PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (pSer181) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
PRKAB1 / AMPK Beta 1 Rabbit anti-Human Polyclonal (aa147-196) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25 of 89 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).