PRDM6

PR domain containing 6

Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression.

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Products

Antibodies (16)

Type

Primary (16)

Target

PRDM6 (16)

Reactivity

Human (16)

Mouse (4)

Rat (4)

Bovine (3)

Chimpanzee (3)

Guinea pig (3)

Horse (3)

Pig (3)

Rabbit (3)

Application

WB (16)

ELISA (6)

Host

rabbit (16)

Isotype

IgG (11)

Clonality

polyclonal pc (16)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa44-72 (7)

C-Terminus (4)

aa448-477 (4)

Publications

No (16)

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PRDM6 Antibody (C-Terminus) LS-C201319

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PRDM6 Antibody (C-Terminus, HRP) LS-C434064

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PRDM6 Antibody (C-Terminus, Biotin) LS-C434061

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PRDM6 Antibody (C-Terminus, FITC) LS-C434062

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Chimpanzee, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PRDM6 Antibody LS-C409395

Antibody:

PRDM6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PRDM6 Antibody (aa44-72) LS-C162122

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PRDM6 Antibody (aa44-72) LS-C324279

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PRDM6 Antibody (aa44-72, Biotin) LS-C239410

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PRDM6 Antibody (aa44-72, FITC) LS-C239411

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PRDM6 Antibody (aa44-72, APC) LS-C239409

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PRDM6 Antibody (aa44-72, PE) LS-C239412

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

PRDM6 Antibody (aa44-72, Azide-free, HRP) LS-C248544

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa44-72) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

PRDM6 Antibody (aa448-477) LS-C82848

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa448-477) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PRDM6 Antibody (aa448-477, HRP) LS-C454439

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa448-477) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PRDM6 Antibody (aa448-477, Biotin) LS-C454438

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa448-477) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PRDM6 Antibody (aa448-477, FITC) LS-C454440

Antibody:

PRDM6 Rabbit anti-Human Polyclonal (aa448-477) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Viewing 1-16 of 16 product results

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