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| Catalog Number | Size | Price |
|---|---|---|
| LS-B5236-125 | 125 µl (0.2 mg/ml) | $695 |
IHC‑plus™ Monoclonal Mouse anti‑Human PR / Progesterone Receptor Antibody (IHC, IF, WB) LS‑B5236
IHC‑plus™ Monoclonal Mouse anti‑Human PR / Progesterone Receptor Antibody (IHC, IF, WB) LS‑B5236
Note: This antibody replaces LS-C9730
Antibody:
PR / Progesterone Receptor Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P, IF, WB, IP
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
PR / Progesterone Receptor Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P, IF, WB, IP
Reactivity:
Human, Monkey, Mouse, Rat
Format:
Unconjugated, Unmodified
Specifications
Description
Progesterone Receptor antibody LS-B5236 is an unconjugated mouse monoclonal antibody to Progesterone Receptor (PR) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 5 publications.
Target
Human PR / Progesterone Receptor
Synonyms
PGR | NR3C3 | PR | Progesterone receptor
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Progesterone Receptor from a human endometrial carcinoma (EnCa 101) grown in athymic mice.
Specificity
Equally recognizes two proteins: 116kD (triplet) and 81kD (singlet) which are identified as the hormone-binding high (B) and low (A) MW forms of human progesterone receptor. This antibody recognizes an epitope in the N-terminal half of human PgR. Species cross-reactivity: baboon, monkey, mouse and rat. Does not cross-react with guinea pig.
Applications
- IHC
- IHC - Paraffin (1:50)
- Immunofluorescence
- Western blot (1 - 2 µg/ml)
- Immunoprecipitation
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation, and Sedimentation in sucrose gradients. Immunoprecipitation (NATIVE ONLY): 2 ug/mg protein lysate Using Protein G. Western Blot: 1-2 ug/ml for 2 hrs at RT. Positive control: T47D cells or breast carcinoma.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 0.2% BSA
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PR / Progesterone Receptor
Validation
Anti-PGR / Progesterone Receptor antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-PGR / Progesterone Receptor antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
See More About...
LSBio Ratings
IHC-plus™ PR / Progesterone Receptor Antibody for IHC, IF/Immunofluorescence, WB/Western, IP LS-B5236 has an LSBio Rating of
Publications (4.4)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (5)
Ovarian stimulation using human chorionic gonadotrophin impairs blastocyst implantation and decidualization by altering ovarian hormone levels and downstream signaling in mice. Ezoe K, Daikoku T, Yabuuchi A, Murata N, Kawano H, Abe T, Okuno T, Kobayashi T, Kato K. Molecular human reproduction. Nov;20:1101-16.
Evaluation of uterine receptivity after gonadotropin releasing hormone agonist administration as an oocyte maturation trigger: a rodent model. Ezoe K, Murata N, Yabuuchi A, Kobayashi T, Kato K. Scientific reports. 2019 August;9:12519.
Immunohistochemistry in Investigative and Toxicologic Pathology. Kyathanahalli S Janardhan, Heather Jensen, Natasha P Clayton, Ronald A Herbert. Toxicologic pathology. 2018 July;46:488-510.
Differentiation Patterns of Uterine Carcinomas and Precursor Lesions Induced by Neonatal Estrogen Exposure in Mice. Alisa A Suen, Wendy N Jefferson, Carmen J Williams, Charles E Wood. Toxicologic pathology. 2018 July;46:574-596.
Uterine Paramesonephric Cysts in Sprague-Dawley Rats from National Toxicology Program Studies. Daven N Jackson-Humbles, John Curtis Seely, Ronald A Herbert, David E Malarkey, Barry S McIntyre, Paul M Foster, Darlene Dixon. Toxicologic pathology. 2018 Jun;46:421-430.
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Mouse
Applications:
Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human, Mouse, Rat
Applications:
IHC, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Reactivity:
Human
Range:
0.313-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
