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Catalog Number Size Price
LS-C42581-50 50 µg (0.98 mg/ml) $410 
Antibody

Polyclonal Rabbit anti‑Human PPARA / PPAR Alpha Antibody (N‑Terminus, WB) LS‑C42581

Polyclonal Rabbit anti‑Human PPARA / PPAR Alpha Antibody (N‑Terminus, WB) LS‑C42581

Antibody:
PPARA / PPAR Alpha Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$410
LS-C42581-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
PPARA / PPAR Alpha Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
PPAR Alpha antibody LS-C42581 is an unconjugated rabbit polyclonal antibody to human PPAR Alpha (PPARA) (N-Terminus). Validated for ELISA and WB.
Target
Human PPARA / PPAR Alpha
Synonyms
PPARA | PPAR Alpha | PPARalpha | PPAR-alpha | NR1C1 | HPPAR | PPAR
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to amino acids 1-18 of human PPAR alpha. (N-TERMINAL).
Epitope
N-Terminus
Specificity
Detects an epitope within the N-terminal region of human peroxisome proliferator-activated receptor, alpha (PPARA), a member of the nuclear hormone receptor subfamily. Upon activation, PPARA forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, fatty acid uptake, and triglyceride catabolism in the liver and skeletal muscle. PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux. PPARA is the main target of fibrate drugs; hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease. They could also be used for the treatment of type II diabetes.
Applications
  • Western blot (1:500 - 1:1000)
  • ELISA (1:8000 - 1:32000)
Usage
Western Blot: LS-C42581 detects a band of approximately 52kD in 3T3 whole cell lysate.
Presentation
PBS, 0.01% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PPARA / PPAR Alpha
Q07869 NM_005036 NP_005027.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/24/2021