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POLR1A

polymerase (RNA) I polypeptide A, 194kDa

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.

Gene Name: polymerase (RNA) I polypeptide A, 194kDa
Synonyms: POLR1A, A190, DKFZP586M0122, RPO14, RNA polymerase I subunit A1, RPA194, RPO1-4
Target Sequences: NM_015425 NP_056240.2 O95602

☰ Filters
Antibodies (12)
Primary (12)
POLR1A (12)
Human (12)
Mouse (2)
Rat (2)
Monkey (1)
WB (11)
ELISA (7)
IP (2)
rabbit (12)
IgG (9)
polyclonal pc (12)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa1437-1465 (7)
Internal (1)
aa1140-1720 (1)
aa1350-1400 (1)
aa1425-1475 (1)
No (12)
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
POLR1A Rabbit anti-Human Polyclonal (aa1140-1720) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
POLR1A Antibody - Detection of human POLR1A/RPA194 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-POLR1A/RPA194 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.
Select
POLR1A Rabbit anti-Human Polyclonal (aa1425-1475) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
POLR1A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
POLR1A Antibody - POLR1A Antibody western blot of A375 cell line lysates (35 ug/lane). The POLR1A antibody detected the POLR1A protein (arrow).
Select
POLR1A Rabbit anti-Human Polyclonal (aa1437-1465) Antibody
Human
WB
Unconjugated
400 µl/$393
POLR1A Antibody - Western blot analysis of POLR1A expression in A375 (A); HEK293T (B); NIH3T3 (C); H9C2 (D) whole cell lysates.
Select
POLR1A Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
Select
POLR1A Rabbit anti-Human Polyclonal (aa1350-1400) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-12 of 12 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).