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PLXNC1 / Plexin C1 is a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.
Gene Name: | plexin C1 |
Synonyms: | PLXNC1, Plexin C1, Plexin-C1, VESPR, Plexin (semaphorin receptor), CD232, CD232 antigen, PLXN-C1 |
Target Sequences: | NM_005761 NP_005752.1 O60486 |
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