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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C501226-50 50 µg $285 
LS-C501226-100 100 µg $385 
Antibody

PIM3 / PIM‑3 Antibody (HRP) LS‑C501226

PIM3 / PIM‑3 Antibody (HRP) LS‑C501226

Antibody:
Rabbit Polyclonal to Human PIM3 / PIM-3
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:
Price
Catalog Number
$285 
LS-C501226-50
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human PIM3 / PIM-3
Application:
ELISA
Reactivity:
Human
Format:
Horseradish Peroxidase, Unmodified
Other formats:

Specifications

Description
PIM-3 antibody LS-C501226 is an HRP-conjugated rabbit polyclonal antibody to human PIM-3 (PIM3 ). Validated for ELISA.
Target
Human PIM3 / PIM-3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA
  • Applications tested for the base form of this product only
Immunogen
Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
Specificity
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PIM3 / PIM-3
Q86V86 SK200D SK200P

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Requested From: United States
Date Requested: 10/15/2019