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PIK3R2 / p85 Beta

phosphoinositide-3-kinase, regulatory subunit 2 (beta)

Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:23604317).

Gene Name: phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Family/Subfamily: Non-Protein Kinase , not assigned-Non-Protein Kinase
Synonyms: PIK3R2, p85, p85B, p85-BETA, PI3K regulatory subunit beta, MPPH, PI3-kinase subunit p85-beta
Target Sequences: NM_005027 NP_005018.1 O00459

☰ Filters
Antibodies (57)
Proteins (3)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Primary (57)
PIK3R2 / p85 Beta (60)
Human (56)
Mouse (18)
Rat (17)
Bat (2)
Bovine (9)
Dog (1)
Guinea pig (1)
Monkey (5)
Pig (2)
Sheep (2)
IHC (30)
IHC-Fr (1)
IHC-P (7)
WB (50)
ELISA (34)
IP (7)
Peptide-ELISA (3)
rabbit (49)
mouse (8)
Product Group
IHCPlus (1)
IgG (39)
IgG1 (6)
IgG2b (1)
monoclonal mc (8)
polyclonal pc (49)
12K162 (1)
T15 (1)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (6)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (5)
Preservative Free (1)
Unconjugated (30)
Tyr464 (7)
Tyr467 (7)
aa1-30 (7)
aa268-298 (7)
pTyr464 (2)
C-Terminus (1)
Gln496 (1)
Internal (1)
aa125-175 (1)
aa409-458 (1)
aa427-463 (1)
aa447-461 (1)
aa447-496 (1)
aa516-642 (1)
aa75-125 (1)
No (60)
6His, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
PIK3R2 / p85 Beta Antibody - PIK3R2 / p85 Beta antibody. IHC(P): Human Breast Cancer Tissue.
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa447-461) Antibody
Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PIK3R2 / p85 Beta Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PIK3R2 / p85 Beta Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with PIK3R2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PIK3R2 / p85 Beta Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
PIK3R2 / p85 Beta Antibody - Immunohistochemistry of paraffin-embedded Human lymphoma using PIK3R2 Polyclonal Antibody at dilution of 1:70.
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (Tyr467) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIK3R2 / p85 Beta Antibody - Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100.
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PIK3R2 / p85 Beta Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
PIK3R2 / p85 Beta Rabbit anti-Human Polyclonal (aa268-298) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Viewing 1-25 of 60 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).