PHAP1 / ANP32A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

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Products

Antibodies (54)

Proteins (8)

Type

Over-Expression Lysate (2)

Primary (54)

Recombinant (6)

Target

PHAP1 / ANP32A (62)

Reactivity

Human (46)

Mouse (25)

Rat (22)

Bovine (3)

Chicken (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (3)

Horse (3)

Monkey (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (31)

IHC-P (19)

WB (50)

ELISA (18)

ICC (3)

IF (10)

IP (2)

Peptide-ELISA (1)

Host

rabbit (51)

mouse (3)

Product Group

IHCPlus (5)

Isotype

IgG (31)

IgG1 (2)

IgG1,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (51)

Clone

2G11-4A5 (1)

8D2 (1)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (25)

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Epitope

aa2-247 (8)

aa2-249 (8)

aa133-162 (7)

N-Terminus (4)

aa121-170 (4)

aa26-55 (2)

C-Terminus (1)

aa1-170 (1)

Publications

No (61)

Yes (1)

Tag

GST (1)

His (2)

His-GST (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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PHAP1 / ANP32A Antibody (aa121-170) LS-B10851

(4.0) Rating

(1) Publication(s)

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa121-170) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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PHAP1 / ANP32A Antibody LS-B133

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$545

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IHC-plus™ PHAP1 / ANP32A Antibody (clone 2G11-4A5) LS-B6170

(4.0) Rating

Antibody:

PHAP1 / ANP32A Mouse anti-Human Monoclonal (2G11-4A5) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ PHAP1 / ANP32A Antibody LS-B3194

(4.0) Rating

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ PHAP1 / ANP32A Antibody LS-B3195

(4.0) Rating

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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PHAP1 / ANP32A Antibody (Preservative Free) LS-C817762

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC-P, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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PHAP1 / ANP32A Antibody LS-C431

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IF, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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PHAP1 / ANP32A Antibody LS-C659517

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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PHAP1 / ANP32A Antibody LS-C334276

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PHAP1 / ANP32A Antibody (clone 8D2) LS-C171326

Antibody:

PHAP1 / ANP32A Mouse anti-Human Monoclonal (8D2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$380

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PHAP1 / ANP32A Antibody LS-C764064

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PHAP1 / ANP32A Antibody (aa2-249) LS-C292599

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa2-249) Antibody

Reactivity:

Rat, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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PHAP1 / ANP32A Antibody (aa26-55) LS-C190991

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa26-55) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$572

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PHAP1 / ANP32A Antibody (aa1-170) LS-C375215

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa1-170) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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PHAP1 / ANP32A Antibody LS-C812496

Antibody:

PHAP1 / ANP32A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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PHAP1 / ANP32A Antibody (aa133-162) LS-C319496

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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PHAP1 / ANP32A Antibody (aa133-162, Biotin) LS-C251392

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PHAP1 / ANP32A Antibody (aa133-162, FITC) LS-C251391

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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PHAP1 / ANP32A Antibody (aa133-162, APC) LS-C251390

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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PHAP1 / ANP32A Antibody (aa133-162, Azide-free, HRP) LS-C251393

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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PHAP1 / ANP32A Antibody (aa133-162, PE) LS-C251395

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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PHAP1 / ANP32A Antibody (N-Terminus) LS-C30659

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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PHAP1 / ANP32A Antibody (aa133-162) LS-C156365

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal (aa133-162) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PHAP1 / ANP32A Antibody LS-C482496

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

Select

PHAP1 / ANP32A Antibody LS-C341861

Antibody:

PHAP1 / ANP32A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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