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| Catalog Number | Size | Price |
|---|---|---|
| LS-A2032-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human PGR1 / GPR153 Antibody (Extracellular Domain, IHC) LS‑A2032
PathPlus™ Polyclonal Rabbit anti‑Human PGR1 / GPR153 Antibody (Extracellular Domain, IHC) LS‑A2032
Antibody:
PGR1 / GPR153 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit
Format:
Unconjugated, Unmodified
Overview
Antibody:
PGR1 / GPR153 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
GPR153 is an Orphan-U GPCR with an unknown ligand. Gpr153 is widely expressed in the central nervous system and peripheral tissues. In situ hybridization on mouse brain showed specifically high expression in the thalamus, cerebellum and the arcuate nucleus. The antisense oligodeoxynucleotide knockdown of Gpr153 caused a slight reduction in food intake and the elevated plus maze test showed significant reduction in the percentage of time spent in the centre square, which points towards a probable role in decision making.
References: FEBS Journal 278(24):4881-94 · December 2011
Target
Human PGR1 / GPR153
Synonyms
GPR153 | PGR1 | G protein-coupled receptor 153
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Bat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR153. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Rabbit, Pig (100%); Bat, Elephant, Panda (94%); Horse (88%); Opossum, Platypus (82%).
Epitope
Extracellular Domain
Specificity
Human GPR153. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR162 (53%).
Applications
- IHC
- IHC - Paraffin (12 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PGR1 / GPR153
Validation
Ovary, Carcinoma
Ovary, Carcinoma
Brain, Medulla, Hypoglossal nucleus
Brain, Medulla, Hypoglossal nucleus
Anti-PGR1 / GPR153 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PGR1 / GPR153 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR153 antibody IHC of human liver, hepatocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR153 antibody IHC of human liver, hepatocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PGR1 / GPR153 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PGR1 / GPR153 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ PGR1 / GPR153 Antibody (Extracellular Domain) for IHC LS-A2032 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Monkey, Bat
Applications:
IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/16/2024
Date Requested: 4/16/2024
