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PDE6D / PDE6 Delta

phosphodiesterase 6D, cGMP-specific, rod, delta

Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.

Gene Name: phosphodiesterase 6D, cGMP-specific, rod, delta
Family/Subfamily: Phosphodiesterase , PDE - photoreceptor
Synonyms: PDE6D, GMP-PDE delta, PDED, Phosphodiesterase 6d, Phosphodiesterase delta, Protein p17, Pde delta
Target Sequences: NM_002601 NP_002592.1 O43924

☰ Filters
Antibodies (21)
Proteins (6)
Over-Expression Lysate (2)
Primary (21)
Recombinant (4)
PDE6D / PDE6 Delta (27)
Human (21)
Mouse (15)
Chimpanzee (3)
Monkey (3)
IHC (7)
IHC-P (2)
WB (19)
ELISA (13)
ICC (1)
IF (1)
rabbit (20)
mouse (1)
IgG (14)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (20)
4H6 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (10)
aa26-55 (7)
aa21-70 (4)
aa1-150 (1)
No (27)
GST (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
PDE6D / PDE6 Delta Protein
Select
E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
PDE6D / PDE6 Delta Antibody - PDE6D Antibody western blot of A2058 cell line lysates (35 ug/lane). The PDE6D antibody detected the PDE6D protein (arrow).
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
PDE6D / PDE6 Delta Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
17.2 kDa
20 µg/$150
PDE6D / PDE6 Delta Protein - Purified recombinant protein PDE6D was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
17.2 kDa
20 µg/$1,107
PDE6D / PDE6 Delta Protein - 12.5% SDS-PAGE of human PDE6D stained with Coomassie Blue
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Wheat Germ Extract
GST
42.24 kDa
10 µg/$479; 25 µg/$670
PDE6D / PDE6 Delta Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using antibody at dilution of 1:100.
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
PDE6D / PDE6 Delta Antibody - IHC of paraffin-embedded SAS xenograft using PDE6D antibody at 1:500 dilution.
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa1-150) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
PDE6D / PDE6 Delta Antibody - Immunofluorescence of monoclonal antibody to PDE6D on HeLa cell . [antibody concentration 10 ug/ml]
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PDE6D / PDE6 Delta Mouse anti-Human Monoclonal (4H6) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa26-55) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
PDE6D / PDE6 Delta Antibody - PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa21-70) Antibody
Human
WB
Unconjugated
100 µl/$424
PDE6D / PDE6 Delta Antibody - PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa21-70) (HRP) Antibody
Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PDE6D / PDE6 Delta Antibody - PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa21-70) (Biotin) Antibody
Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PDE6D / PDE6 Delta Antibody - PDE6D / PDE6 Delta antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal (aa21-70) (FITC) Antibody
Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PDE6D / PDE6 Delta Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using PDE6D Polyclonal Antibody at dilution of 1:50(×200)
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PDE6D / PDE6 Delta Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using PDE6D Polyclonal Antibody at dilution of 1:60(×200)
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PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PDE6D / PDE6 Delta Antibody - Western blot analysis of extracts of various cell lines, using PDE6D antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
PDE6D / PDE6 Delta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).