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PDE6A / PDE6 Alpha

phosphodiesterase 6A, cGMP-specific, rod, alpha

PDE6A is the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Gene Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Family/Subfamily: Phosphodiesterase , PDE - photoreceptor
Synonyms: PDE6A, Alpha-PDE, CGMP phosphodiesterase alpha, CGPR-A, PDE6alpha, PDE V-B1, PDEA, Phosphodiesterase 6a, RP43, GMP-PDE alpha
Target Sequences: NM_000440 NP_000431.2 P16499

☰ Filters
Antibodies (18)
Proteins (3)
Over-Expression Lysate (2)
Primary (18)
Recombinant (1)
PDE6A / PDE6 Alpha (21)
Human (18)
Mouse (7)
Rat (7)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Hamster (4)
Horse (3)
Monkey (1)
Orangutan (3)
Zebrafish (3)
IHC (5)
IHC-P (3)
WB (16)
ELISA (8)
IF (1)
Peptide-ELISA (1)
rabbit (18)
Product Group
IHCPlus (1)
IgG (12)
polyclonal pc (18)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa308-336 (7)
aa99-148 (4)
N-Terminus (1)
No (21)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
PDE6A / PDE6 Alpha Antibody - Anti-PDE6A / PDE6 Alpha antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PDE6A / PDE6 Alpha Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PDE6A / PDE6 Alpha Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
PDE6A / PDE6 Alpha Antibody - 1:100 staining human pancreas carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) Antibody
Human
WB
Unconjugated
200 µl/$734
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PDE6A / PDE6 Alpha Antibody - Western blot of Human Fetal Thymus. PDE6A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) Antibody
Human
WB
Unconjugated
100 µl/$424
PDE6A / PDE6 Alpha Antibody - Western blot of Human Fetal Thymus. PDE6A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (HRP) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Antibody - Western blot of Human Fetal Thymus. PDE6A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (Biotin) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Antibody - Western blot of Human Fetal Thymus. PDE6A antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (FITC) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Antibody - PDE6A Antibody western blot of K562 cell line lysates (35 ug/lane). The PDE6A antibody detected the PDE6A protein (arrow).
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) Antibody
Human
WB
Unconjugated
400 µl/$393
PDE6A / PDE6 Alpha Antibody - Western blot analysis of extracts of various cells.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PDE6A / PDE6 Alpha Antibody - Western blot analysis of extracts of various cell lines using PDE6A Polyclonal Antibody at dilution of 1:1000.
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PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PDE6A / PDE6 Alpha Protein
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E. coli
His, N-Terminal
99.4 kDa
50 µg/$419
PDE6A / PDE6 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
99.4 kDa
100 µg/$494
PDE6A / PDE6 Alpha Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
99.4 kDa
20 µg/$150
Viewing 1-21 of 21 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).