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PDE4C

phosphodiesterase 4C, cAMP-specific

PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: phosphodiesterase 4C, cAMP-specific
Family/Subfamily: Phosphodiesterase , PDE - cAMP-specific
Synonyms: PDE4C, DPDE1, Pde-ivc, PDE21, Phosphodiesterase 4c, Pde4c2
Target Sequences: NM_000923 AAD47053.1 Q08493

Publications (1)

1
Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia. Mahmood B, Damm MM, Jensen TS, Backe MB, Dahllöf MS, Poulsen SS, Bindslev N, Hansen MB. BMC cancer. 2016 16:938. (IHC; Human) [Full Text Article] [PubMed:27927168] [PMC:PMC5141637] Related Antibodies: LS-C185777.

☰ Filters
Antibodies (21)
Proteins (7)
Over-Expression Lysate (5)
Primary (21)
Recombinant (2)
PDE4C (28)
Human (21)
Mouse (10)
Rat (11)
Bat (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
IHC (1)
IHC-P (1)
WB (21)
ELISA (9)
ICC (1)
IF (2)
IP (1)
Peptide-ELISA (3)
rabbit (20)
mouse (1)
IgG (13)
IgG3,k (1)
monoclonal mc (1)
polyclonal pc (20)
4E5 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
aa5-31 (6)
aa457-506 (4)
260-340 aa, Internal (1)
Internal (1)
aa274-323 (1)
aa291-340 (1)
aa325-667 (1)
aa333-378 (1)
No (27)
Yes (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
PDE4C Antibody - IHC of paraffin-embedded endo mitral using PDE4C antibody at 1:100 dilution.
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PDE4C Rabbit anti-Human Polyclonal (aa325-667) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
PDE4C Antibody - Immunofluorescence of monoclonal antibody to PDE4C on HeLa cell . [antibody concentration 10 ug/ml]
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PDE4C Mouse anti-Human Monoclonal (4E5) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
PDE4C Antibody - Staining A549 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PDE4C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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PDE4C Rabbit anti-Human Polyclonal (aa333-378) Antibody
Mouse, Rat, Human
ICC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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PDE4C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
PDE4C Antibody - Western blot of PDE4C antibody
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PDE4C Rabbit anti-Human Polyclonal (260-340 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PDE4C Antibody - Western blot analysis of extracts from A549 cells, RAW264.7 cells and HuvEc cells, using PDE4C antibody.
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PDE4C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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PDE4C Rabbit anti-Human Polyclonal (aa291-340) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PDE4C Antibody - Western blot analysis of the lysates from HeLa cells using PDE4C antibody.
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PDE4C Rabbit anti-Human Polyclonal (aa274-323) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PDE4C Antibody - Western blot analysis of PDE4C expression in HEK293T (A); SHSY5Y (B) whole cell lysates.
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PDE4C Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
100 µl/$299
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PDE4C Rabbit anti-Human Polyclonal (aa5-31) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
PDE4C Rabbit anti-Human Polyclonal (aa5-31) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
PDE4C Rabbit anti-Human Polyclonal (aa5-31) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
PDE4C Rabbit anti-Human Polyclonal (aa5-31) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
PDE4C Rabbit anti-Human Polyclonal (aa5-31) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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PDE4C Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PDE4C Antibody - PDE4C antibody Western Blot of Fetal Lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE4C Rabbit anti-Human Polyclonal (aa457-506) Antibody
Human
WB
Unconjugated
100 µl/$424
PDE4C Antibody - PDE4C antibody Western Blot of Fetal Lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE4C Rabbit anti-Human Polyclonal (aa457-506) (HRP) Antibody
Mouse, Dog, Rat, Bat, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
PDE4C Antibody - PDE4C antibody Western Blot of Fetal Lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PDE4C Rabbit anti-Human Polyclonal (aa457-506) (Biotin) Antibody
Mouse, Dog, Rat, Bat, Gibbon, Chimpanzee, Human
WB
Biotin Conjugated
100 µl/$469
PDE4C Antibody - PDE4C antibody Western Blot of Fetal Lung.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PDE4C Rabbit anti-Human Polyclonal (aa457-506) (FITC) Antibody
Mouse, Dog, Rat, Bat, Gibbon, Chimpanzee, Human
WB
FITC Conjugated
100 µl/$469
PDE4C Antibody - PDE4C Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The PDE4C antibody detected the PDE4C protein (arrow).
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PDE4C Rabbit anti-Human Polyclonal (aa5-31) Antibody
Human
WB
Unconjugated
400 µl/$393
PDE4C Protein - Purified recombinant protein PDE4C was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
67.6 kDa
20 µg/$1,107
PDE4C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
75.4 kDa
100 µg/$710
PDE4C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
67.6 kDa
100 µg/$710
PDE4C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
75.4 kDa
20 µg/$215
Viewing 1-25 of 28 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).