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PC / Pyruvate Carboxylase

pyruvate carboxylase

PC / Pyruvate Carboxylase is pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

Gene Name: pyruvate carboxylase
Synonyms: PC, PCB, Pyruvate carboxylase, Pyruvic carboxylase
Target Sequences: NM_000920 NP_000911.2 P11498

☰ Filters
Antibodies (47)
ELISA Kits (8)
Proteins (8)
Custom (4)
Over-Expression Lysate (4)
Primary (47)
Recombinant (4)
Sandwich (4)
PC / Pyruvate Carboxylase (63)
Human (38)
Mouse (26)
Rat (16)
Bat (1)
Bovine (3)
Chicken (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (4)
Maize (2)
Monkey (2)
Pig (14)
Rabbit (1)
Sheep (1)
Yeast (4)
Zebrafish (1)
IHC (22)
IHC-P (9)
WB (43)
ELISA (20)
ICC (5)
ID (2)
IE (2)
IF (8)
IP (1)
Peptide-ELISA (4)
rabbit (46)
goat (1)
Product Group
IHCPlus (2)
IgG (24)
polyclonal pc (47)
96-Well Strip Plate (8)
APC (1)
APC Conjugated (2)
Biotin Conjugated (7)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (21)
aa36-486 (8)
aa53-82 (7)
aa930-1050 (4)
aa981-1030 (4)
330-410 aa, Internal (1)
Internal (1)
aa341-390 (1)
aa357-406 (1)
aa400-445 (1)
aa74-371 (1)
aa886-899 (1)
No (62)
Yes (1)
Cell Lysates (1)
Plasma (2)
Serum (2)
Tissue Homogenates (3)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
PC / Pyruvate Carboxylase Antibody - Anti-Pyruvate Carboxylase antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PC / Pyruvate Carboxylase Goat anti-Human Polyclonal (aa886-899) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
PC / Pyruvate Carboxylase Antibody - PC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa53-82) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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PC / Pyruvate Carboxylase Rabbit anti-Yeast Polyclonal Antibody
Yeast
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
PC / Pyruvate Carboxylase Protein - Recombinant  Pyruvate Carboxylase By SDS-PAGE
Select
E. coli
His-T7
53.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
PC / Pyruvate Carboxylase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using PC Antibody at dilution of 1:100
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
PC / Pyruvate Carboxylase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
PC / Pyruvate Carboxylase Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
PC / Pyruvate Carboxylase Antibody - Western blot analysis of Pyruvate Carboxylase expression in HEK293T (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$299
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Bovine, Rat, Pig, Human
ICC, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa930-1050) (Biotin) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa930-1050) (DY488) Antibody
Human
ICC, IF, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa930-1050) (DY650) Antibody
Human
ICC, IF, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry: Pyruvate Carboxylase Antibody - Analysis of Pyruvate Carboxylase in mouse kidney and mouse fat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa930-1050) (DY550) Antibody
Human
ICC, IF, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
PC / Pyruvate Carboxylase Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PC / Pyruvate Carboxylase Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using PC Antibody. The picture on the right is blocked with the synthesized peptide.
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa357-406) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa53-82) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PC / Pyruvate Carboxylase Rabbit anti-Mouse Polyclonal (aa53-82) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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PC / Pyruvate Carboxylase Rabbit anti-Mouse Polyclonal (aa53-82) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PC / Pyruvate Carboxylase Rabbit anti-Mouse Polyclonal (aa53-82) (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PC / Pyruvate Carboxylase Rabbit anti-Mouse Polyclonal (aa53-82) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PC / Pyruvate Carboxylase Rabbit anti-Mouse Polyclonal (aa53-82) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (330-410 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PC / Pyruvate Carboxylase Antibody
Select
PC / Pyruvate Carboxylase Rabbit anti-Human Polyclonal (aa74-371) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
Viewing 1-25 of 63 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).