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PARP3

poly (ADP-ribose) polymerase family, member 3

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Gene Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: PARP3, ADPRT-3, ADPRTL2, ADPRTL3, ARTD3, ADPRT3, HPARP-3, PADPRT-3, Poly[ADP-ribose] synthase 3, Poly[ADP-ribose] synthetase 3, PARP-3, Poly [ADP-ribose] polymerase 3, IRT1, NAD+ ADP-ribosyltransferase 3, Poly(ADP-ribose) synthetase-3
Target Sequences: NM_005485 NP_005476.4 Q9Y6F1

☰ Filters
Antibodies (22)
Proteins (8)
Over-Expression Lysate (4)
Primary (22)
Recombinant (4)
PARP3 (30)
Human (22)
Mouse (4)
Rat (2)
Chimpanzee (3)
Horse (3)
Monkey (3)
Rabbit (3)
IHC (15)
IHC-P (10)
WB (13)
ELISA (10)
IF (3)
Peptide-ELISA (2)
rabbit (21)
goat (1)
Product Group
IHCPlus (2)
IgG (17)
polyclonal pc (22)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (16)
aa446-495 (4)
aa294-533 (2)
10-90 aa, N-terminal (1)
N-Terminus (1)
aa10-59 (1)
aa451-481 (1)
aa90-104 (1)
aa99-126 (1)
No (30)
GST (1)
His (1)
His-GST (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
Baculovirus (1)
HEK 293 Cells (3)
Sf21 Cells (1)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
Biologically active (1)
PARP3 Antibody - Western blot of anti-PARP3 antibody in mouse spleen tissue lysates (35 ug/lane). PARP3(arrow) was detected using the purified antibody.
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PARP3 Rabbit anti-Mouse Polyclonal (aa451-481) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
PARP3 Antibody - PARP3 Antibody western blot of K562,MDA-MB453,NCI-H292,A549,293,HeLa,CEM,NCI-H460 cell line and human normal uterus tissue lysates (35 ug/lane). The PARP3 antibody detected the PARP3 protein (arrow).
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PARP3 Rabbit anti-Human Polyclonal (aa99-126) Antibody
Human
WB
Unconjugated
400 µl/$393
PARP3 Antibody - Anti-PARP3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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PARP3 Rabbit anti-Human Polyclonal (aa10-59) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
PARP3 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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PARP3 Rabbit anti-Human Polyclonal (aa294-533) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PARP3 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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PARP3 Rabbit anti-Human Polyclonal (aa294-533) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PARP3 Antibody - Anti-PARP3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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PARP3 Goat anti-Human Polyclonal (aa90-104) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
PARP3 Antibody - Immunohistochemistry Dilution at 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PARP3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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PARP3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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PARP3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PARP3 Antibody - Immunofluorescence analysis of MCF7 cells.
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PARP3 Antibody - PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PARP3 Rabbit anti-Human Polyclonal (aa446-495) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
PARP3 Antibody - PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PARP3 Rabbit anti-Human Polyclonal (aa446-495) (HRP) Antibody
Rabbit, Horse, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PARP3 Antibody - PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PARP3 Rabbit anti-Human Polyclonal (aa446-495) (Biotin) Antibody
Rabbit, Horse, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PARP3 Antibody - PARP3 antibody ARP33760_P050-NP_005476-PARP3 (poly (ADP-ribose) polymerase family, member 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PARP3 Rabbit anti-Human Polyclonal (aa446-495) (FITC) Antibody
Rabbit, Horse, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
PARP3 Antibody - Immunohistochemical analysis of PARP3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PARP3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
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PARP3 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PARP3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using PARP3 antibody.
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
PARP3 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using PARP3 Polyclonal Antibody at dilution of 1:40.
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PARP3 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PARP3 Antibody - Western blot of PARP3 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: RAW264.7 whole cell lysate.
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PARP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$431
PARP3 Protein - Purified recombinant protein PARP3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
59.9 kDa
20 µg/$1,107
PARP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.9 kDa
20 µg/$150
PARP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.9 kDa
20 µg/$150
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).