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PACSIN2

protein kinase C and casein kinase substrate in neurons 2

Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Gene Name: protein kinase C and casein kinase substrate in neurons 2
Synonyms: PACSIN2, SDPII, Syndapin II
Target Sequences: NM_007229 NP_009160.2 Q9UNF0

Publications (1)

1
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. de Kreuk BJ, Nethe M, Fernandez-Borja M, Anthony EC, Hensbergen PJ, Deelder AM, Plomann M, Hordijk PL. Journal of cell science. 2011 124:2375-88. [PubMed:21693584] Related Antibodies: LS-C101183.

☰ Filters
Antibodies (17)
Proteins (9)
Over-Expression Lysate (4)
Primary (17)
Recombinant (5)
PACSIN2 (26)
Human (17)
Mouse (12)
Rat (1)
Bovine (1)
Chicken (1)
Dog (1)
Xenopus (1)
IHC (13)
IHC-P (5)
WB (17)
ELISA (11)
ICC (5)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (15)
mouse (2)
Product Group
IHCPlus (1)
IgG (12)
IgG1,k (1)
IgG2a,k (1)
monoclonal mc (2)
polyclonal pc (15)
1735CT116.76.60 (1)
3D6 (1)
APC Conjugated (1)
Azide-free (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa342-371 (7)
aa400-450 (1)
No (25)
Yes (1)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (7)
293T Cells (2)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
PACSIN2 Antibody - Immunohistochemical of paraffin-embedded H.stomach section using PACSIN2 Antibody. Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PACSIN2 Antibody - Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PACSIN2 Rabbit anti-Human Polyclonal (aa400-450) Antibody
Xenopus, Chicken, Bovine, Mouse, Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
PACSIN2 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
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PACSIN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PACSIN2 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
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PACSIN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PACSIN2 Antibody - Immunoperoxidase of monoclonal antibody to PACSIN2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
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PACSIN2 Mouse anti-Human Monoclonal (3D6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
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PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (Biotin) Antibody
Mouse, Human
ELISA, ICC, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (FITC) Antibody
Mouse, Human
ELISA, ICC, IHC, WB
FITC Conjugated
200 µl/$952
Select
PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (Azide-free) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated, Azide-free
200 µl/$734
Select
PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (APC) Antibody
Mouse, Human
ELISA, ICC, IHC, WB
APC Conjugated
200 µl/$952
Select
PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, ICC, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PACSIN2 Rabbit anti-Human Polyclonal (aa342-371) (PE) Antibody
Mouse, Human
ELISA, ICC, IHC, WB
PE Conjugated
200 µl/$952
Select
PACSIN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
PACSIN2 Antibody - Western blot analysis of extracts of various cells.
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PACSIN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PACSIN2 Antibody - All lanes: Anti-PACSIN2 Antibody at 1:2000 dilution Lane 1: Daudi whole cell lysate Lane 2: HL-60 whole cell lysate Lane 3: human brain lysate Lane 4: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 56 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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PACSIN2 Mouse anti-Human Monoclonal (1735CT116.76.60) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$393
PACSIN2 Antibody - Western blot analysis of extracts of NIH-3T3 cells using PACSIN2 antibody. The lane on the left was treated with blocking peptide.
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PACSIN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PACSIN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PACSIN2 Antibody - Western blot analysis of Syndapin-2 expression in HepG2 (A); mouse lung (B); mouse heart (C) whole cell lysates.
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PACSIN2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PACSIN2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
PACSIN2 Protein - Purified recombinant protein PACSIN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.6 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
55.6 kDa
20 µg/$150
PACSIN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51.8 kDa
20 µg/$150
PACSIN2 Protein - 12.5% SDS-PAGE of human PACSIN2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
82.1 kDa
10 µg/$479; 25 µg/$670
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
56.7 kDa
10 µg/$317; 50 µg/$524
PACSIN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.8 kDa
100 µg/$494
Viewing 1-25 of 26 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).