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P2RY6 / P2Y6

pyrimidinergic receptor P2Y, G-protein coupled, 6

P2RY6 / P2Y6 belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene Name: pyrimidinergic receptor P2Y, G-protein coupled, 6
Family/Subfamily: GPCR , Purinergic
Synonyms: P2RY6, G-coupled nucleotide receptor, p2 purinoceptor, p2y3 receptor, p2Y purinoceptor 6, Purinergic receptor p2y6, p2RY6, p2y3 and chick, p2Y6 receptor, p2Y6, Purinoceptor p2y6
Target Sequences: NM_004154 NP_004145.1 Q15077

Publications (1)

1
Altered purinergic receptor-Ca²? signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells. Azimi I, Beilby H, Davis FM, Marcial DL, Kenny PA, Thompson EW, Roberts-Thomson SJ, Monteith GR. Molecular oncology. 2016 January;10:166-78. (Human) [Full Text Article] [PubMed:26433470] [PMC:PMC5528926]

☰ Filters
Antibodies (19)
Proteins (10)
Over-Expression Lysate (8)
Primary (19)
Recombinant (2)
P2RY6 / P2Y6 (29)
Human (19)
Mouse (3)
Rat (6)
Bat (3)
Bovine (4)
Chimpanzee (3)
Gibbon (3)
Hamster (1)
Monkey (5)
Orangutan (3)
Pig (4)
Rabbit (4)
IHC (5)
IHC-P (3)
WB (17)
ELISA (9)
ICC (1)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (19)
Product Group
GPCR Database Antibodies (2)
PathPlus Neuro (2)
IgG (11)
polyclonal pc (19)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (11)
aa286-314 (7)
aa109-158 (4)
C-Terminus (1)
Cytoplasmic Domain (1)
No (29)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (8)
Human (6)
293T Cells (4)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
P2RY6 / P2Y6 Antibody - Anti-P2RY6 / P2Y6 antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
P2RY6 / P2Y6 Antibody - Anti-P2RY6 / P2Y6 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Bovine, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
P2RY6 / P2Y6 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) Antibody
Human
WB
Unconjugated
100 µl/$424
P2RY6 / P2Y6 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (HRP) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
P2RY6 / P2Y6 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (Biotin) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
P2RY6 / P2Y6 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (FITC) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
P2RY6 / P2Y6 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
P2RY6 / P2Y6 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue, using P2RY6 antibody.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
P2RY6 / P2Y6 Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using P2RY6 Polyclonal Antibody at dilution of 1:40(×200)
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
P2RY6 / P2Y6 Antibody - Immunochemical staining of human P2RY6 in human kidney with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
P2RY6 / P2Y6 Antibody - P2RY6 Antibody western blot of 293 cell line lysates (35 ug/lane). The P2RY6 antibody detected the P2RY6 protein (arrow).
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P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) Antibody
Human
WB
Unconjugated
400 µl/$393
P2RY6 / P2Y6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
P2RY6 / P2Y6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
P2RY6 / P2Y6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
P2RY6 / P2Y6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
P2RY6 / P2Y6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
36.2 kDa
20 µg/$150
P2RY6 / P2Y6 Protein - 12.5% SDS-PAGE of human P2RY6 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.8 kDa
2 µg/$439
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).