Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

P2RY12 / P2Y12

purinergic receptor P2Y, G-protein coupled, 12

P2RY12 / P2Y12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Gene Name: purinergic receptor P2Y, G-protein coupled, 12
Family/Subfamily: GPCR , Purinergic
Synonyms: P2RY12, ADP-glucose receptor, ADPG-R, p2Y(12)R, p2Y(ADP), p2T(AC), p2Y12, Platelet ADP receptor, SP1999, p2RY12, p2Y purinoceptor 12, Purinergic receptor P2RY12, BDPLT8, Gi-coupled ADP receptor HORK3, HORK3, p2Y(AC), p2Y(cyc), p2Y12 platelet ADP receptor
Target Sequences: NM_022788 NP_073625.1 Q9H244

Publications (1)

1
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake. Santra Brenna, Hermann C Altmeppen, Behnam Mohammadi, Björn Rissiek, Florence Schlink, Peter Ludewig, Christoph Krisp, Hartmut Schlüter, Antonio Virgilio Failla, Carola Schneider, Markus Glatzel, Berta Puig, Tim Magnus. Journal of Extracellular Vesicles. 2020 August;9:1809065. [Full Text Article] [PubMed:32944194] [PMC:PMC7480459]

☰ Filters
Antibodies (7)
Proteins (6)
ELISA Kits (5)
Custom (1)
Over-Expression Lysate (4)
Primary (7)
Recombinant (2)
Sandwich (4)
P2RY12 / P2Y12 (18)
Human (10)
Mouse (4)
Rat (4)
Dog (1)
Horse (1)
Monkey (1)
Rabbit (1)
IHC (3)
IHC-P (3)
WB (4)
Flo (1)
ELISA (2)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (6)
mouse (1)
Product Group
GPCR Database Antibodies (2)
IHCPlus (1)
PathPlus Cancer (1)
IgG (4)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (6)
1C2A9 (1)
96-Well Strip Plate (5)
Unconjugated (7)
Extracellular Domain (1)
N-Terminus (1)
No (18)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (3)
10His, N-terminus (1)
Myc-DDK (Flag) (5)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
P2RY12 / P2Y12 Antibody - Anti-P2RY12 / P2Y12 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Cancer
Fast Shipping
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
P2RY12 / P2Y12 Antibody - Anti-P2RY12 / P2Y12 antibody IHC of human bone marrow, megakaryocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Rabbit, Dog, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
P2RY12 / P2Y12 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Select
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
P2RY12 / P2Y12 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
P2RY12 / P2Y12 Antibody - 1:200 staining rat brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
P2RY12 / P2Y12 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
P2RY12 / P2Y12 Antibody - Western blot analysis using P2RY12 mAb against human P2RY12 (AA: extra mix) recombinant protein. (Expected MW is 9.4 kDa)
Select
P2RY12 / P2Y12 Mouse anti-Human Monoclonal (1C2A9) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
P2RY12 / P2Y12 Protein - Purified recombinant protein P2RY12 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.3 kDa
20 µg/$1,107
P2RY12 / P2Y12 Antibody - Western blot analysis of extracts of various cell lines, using P2RY12 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 180s.
Select
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
P2RY12 / P2Y12 Antibody - Anti-Human P2Y12 Receptor staining (10 µg/ml) of a human bone marrow formalin-fixed, paraffin-embedded tissue section; seen at 20x magnification. Staining of bone marrow cells and interstitium is observed.
Select
P2RY12 / P2Y12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
100 µg/$491
P2RY12 / P2Y12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.3 kDa
20 µg/$150
P2RY12 / P2Y12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
39.3 kDa
20 µg/$150
P2RY12 / P2Y12 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
P2RY12 / P2Y12 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
P2RY12 / P2Y12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.3 kDa
100 µg/$494
P2RY12 / P2Y12 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
39.3 kDa
100 µg/$494
Select
E. coli
10His, N-terminus
100 µg/$1,801; 20 µg/$1,247
Viewing 1-18 of 18 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).