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OSMR / IL-31R-Beta

oncostatin M receptor

OSMR / IL-31R-Beta is a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: oncostatin M receptor
Synonyms: OSMR, IL-31R-beta, IL-31R subunit beta, PLCA1, Oncostatin M receptor, OSMRB, IL-31 receptor subunit beta, IL-31RB
Target Sequences: NM_003999 NP_003990.1 Q99650

Publications (4)

1
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November; [Full Text Article] [PubMed:33236123] Related Antibodies: LS-B11477.
2
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3. [Full Text Article] [PubMed:31626785] Related Antibodies: LS-B11477.
3
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810. [Full Text Article] [PubMed:33428793] Related Antibodies: LS-B11477.
4
SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Robson MJ, Turner RC, Naser ZJ, McCurdy CR, O'Callaghan JP, Huber JD, Matsumoto RR. Experimental neurology. 2014 254:180-9. (WB; Human) [Full Text Article] [PubMed:24508558] [PMC:PMC4241368] Related Antibodies: LS-C73895.
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Antibodies (54)
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OSMR / IL-31R-Beta (84)
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OSMR / IL-31R-Beta Antibody - Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Antibody - Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (HRP) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
OSMR / IL-31R-Beta Antibody - Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (Biotin) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
OSMR / IL-31R-Beta Antibody - Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (FITC) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
OSMR / IL-31R-Beta Antibody - Western blot analysis of extracts of various cell lines.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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OSMR / IL-31R-Beta Rat anti-Mouse Monoclonal (aa24-738) (PE) (12K147) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$836
OSMR / IL-31R-Beta Antibody - Staining of the Jurkat (left) and A375 (right) cell lines with PE Mouse IgG1, K isotype control (blue histogram) or PE Anti-human oncostatin M receptor (OSMR) (purple histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (PE) (AN-V2) Antibody
Human
Flo
PE Conjugated
100 Tests/$453
OSMR / IL-31R-Beta ELISA Kit
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Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
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OSMR / IL-31R-Beta Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
OSMR / IL-31R-Beta Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa513-760) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Antibody - Western blot of OSMR / IL-31R-Beta antibody.
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OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal (aa410-652) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
OSMR / IL-31R-Beta Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (8F3H8B2) Antibody
Human
ELISA, IHC-P, IP
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution of 1:100
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo
Unconjugated
20 µl/$271; 100 µl/$412
Select
OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
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OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (aa28-739) (APC) (10K58 ) Antibody
Human
Flo
APC Conjugated
100 Tests/$890
OSMR / IL-31R-Beta Antibody - HT1080 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 8%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa21-70) Antibody
Human
WB
Unconjugated
100 µl/$424
OSMR / IL-31R-Beta Antibody - HT1080 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 8%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa21-70) (FITC) Antibody
Dog, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
OSMR / IL-31R-Beta Protein - Recombinant Oncostatin M Receptor By SDS-PAGE
Select
E. coli
His-T7
31.5 kDa
10 µg/$274; 50 µg/$397; 100 µg/$635; 200 µg/$792; 1 mg/$1,864; 500 µg/$1,419; 5 mg/$2,826; 2 mg/$2,047
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
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OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Antibody - Western blot analysis of extracts of A375 cells using OSMR antibody. The lane on the left was treated with blocking peptide.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$351
Select
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Viewing 1-25 of 84 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).