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| Catalog Number | Size | Price |
|---|---|---|
| LS-C388989-100 | 100 µg | $575 |
Polyclonal Rabbit anti‑Human NR1H3 / LXR Alpha Antibody (aa375‑398, WB) LS‑C388989
Polyclonal Rabbit anti‑Human NR1H3 / LXR Alpha Antibody (aa375‑398, WB) LS‑C388989
Antibody:
NR1H3 / LXR Alpha Rabbit anti-Human Polyclonal (aa375-398) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
NR1H3 / LXR Alpha Rabbit anti-Human Polyclonal (aa375-398) Antibody
Application:
WB
Reactivity:
Human, Mouse, Rat, Hamster
Format:
Unconjugated, Unmodified
Specifications
Description
LXR Alpha antibody LS-C388989 is an unconjugated rabbit polyclonal antibody to LXR Alpha (NR1H3) (aa375-398) from human. It is reactive with human, mouse, rat and other species. Validated for WB.
Target
Human NR1H3 / LXR Alpha
Synonyms
NR1H3 | Liver X receptor alpha | LXRA | LXR-a | Oxysterols receptor LXR-alpha | LXR alpha | Lxralpha | RLD-1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Hamster
(tested or 100% immunogen sequence identity)
Predicted
Bat, Bovine, Dog, Goat, Guinea pig, Horse, Pig, Rabbit, Sheep (at least 90% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide (QVERLQHTYVEALHAYVSINHPHD, aa375-398) was used as the immunogen for this NR1H3 antibody (100% homologous in human, mouse and rat). Percent identity by BLAST analysis: Mouse, Rat, Hamster (100%); Human, Ferret, Sheep, Cat, Bovine, Bat, Goat, Elephant, Rabbit, Horse, Pig, Dog (96%); Opossum, Guinea pig (92%); Platypus (88%).
Epitope
aa375-398
Specificity
Human NR1H3 / LXR Alpha
Applications
- Western blot (0.5 - 1 µg/ml)
Usage
LXR (Liver X Receptor) alpha, also known as NR1H3, is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NR1H3 / LXR Alpha
Publications (0)
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Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Rat
Applications:
IHC, Western blot, Immunoprecipitation, ELISA
Species:
Human, Rat
Applications:
Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Reactivity:
Human
Range:
0.312-20 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
