NR0B1 / DAX1

nuclear receptor subfamily 0, group B, member 1

DAX-1 (DSS-AHC critical region on the X chromosome, gene 1) is an orphan NRO Knirps-Like nuclear receptor that is involved in adrenal gland and gonad development. DAX-1 has been shown to negatively regulate transcription of the nuclear receptor steroidogenic factor 1 (SF-1). DAX-1 is also involved in the development and differentiation of anterior pituitary cells and in steroidogenesis. In the nucleus, DAX-1 binds to a retinoic acid-responsive element (RARE) and acts as a dominant-negative regulator of retinoic acid receptor-mediated transcription. DAX-1 gene transcription is regulated by Ad4BP/SF-1 (NR5A1) and is suppressed by androgens and the androgen receptor (AR/NR3C4); AR down-regulated DAX-1 gene transcription is mediated by Ad4BP/SF-1 in the presence of the ligand. Recently it has been shown that DAX-1 is required for testis development (Meeks et al. 2003). Mutations in the human DAX-1 gene lead to X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Recently two isoforms of DAX-1 has been identified.

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Products

Antibodies (60)

Proteins (7)

Type

Over-Expression Lysate (2)

Primary (60)

Recombinant (5)

Target

NR0B1 / DAX1 (67)

Reactivity

Human (59)

Mouse (11)

Rat (8)

Bovine (3)

Chicken (3)

Chimpanzee (15)

Dog (6)

Gibbon (9)

Guinea pig (3)

Horse (3)

Monkey (10)

Orangutan (12)

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Zebrafish (3)

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Application

IHC (27)

IHC-P (17)

WB (51)

ELISA (26)

ICC (2)

IF (5)

IP (1)

Peptide-ELISA (2)

Host

rabbit (56)

mouse (3)

goat (1)

Product Group

IHCPlus (5)

Isotype

IgG (43)

IgG1 (2)

IgG2a,k (1)

Clonality

monoclonal mc (3)

polyclonal pc (57)

Clone

2F12 (1)

OTI5F5 (2)

Format

APC Conjugated (3)

Azide-free (3)

Biotin Conjugated (9)

Carrier-free (1)

FITC Conjugated (9)

HRP Conjugated (9)

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Preservative Free (1)

Unconjugated (27)

Epitope

aa304-333 (14)

aa4-34 (7)

N-Terminus (5)

aa151-200 (4)

aa201-250 (4)

aa359-408 (4)

aa401-450 (4)

aa161-430 (2)

C-Terminus (1)

Ligand-binding Domain (1)

aa202-214 (1)

aa96-406 (1)

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Publications

No (66)

Yes (1)

Tag

GST (1)

GST, N-terminus (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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NR0B1 / DAX1 Antibody (aa359-408) LS-B3480

(4.0) Rating

(1) Publication(s)

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa359-408) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ NR0B1 / DAX1 Antibody (Ligand-binding Domain) LS-A5732

Fast Shipping

(4.0) Rating

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (Ligand-binding Domain) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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NR0B1 / DAX1 Antibody LS-C335176

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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IHC-plus™ NR0B1 / DAX1 Antibody (C-Terminus) LS-A5716

Fast Shipping

(4.0) Rating

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ NR0B1 / DAX1 Antibody (N-Terminus) LS-A5703

Fast Shipping

(4.0) Rating

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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NR0B1 / DAX1 Antibody (aa151-200) LS-C40520

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa151-200) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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NR0B1 / DAX1 Antibody (aa202-214) LS-C54704

Antibody:

NR0B1 / DAX1 Goat anti-Human Polyclonal (aa202-214) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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NR0B1 / DAX1 Antibody LS-C809558

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NR0B1 / DAX1 Antibody (aa96-406) LS-C185691

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa96-406) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$450

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NR0B1 / DAX1 Antibody LS-C678856

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IHC-plus™ NR0B1 / DAX1 Antibody (aa304-333) LS-B9030

(4.0) Rating

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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NR0B1 / DAX1 Antibody (aa304-333) LS-C162981

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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NR0B1 / DAX1 Antibody LS-C664990

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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NR0B1 / DAX1 Antibody (aa304-333) LS-C323432

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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NR0B1 / DAX1 Antibody (aa304-333, Biotin) LS-C264691

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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NR0B1 / DAX1 Antibody (aa304-333, FITC) LS-C264692

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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NR0B1 / DAX1 Antibody (aa304-333, APC) LS-C264690

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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NR0B1 / DAX1 Antibody (aa304-333, Azide-free, HRP) LS-C264693

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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NR0B1 / DAX1 Antibody (aa304-333, PE) LS-C264695

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (aa304-333) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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NR0B1 / DAX1 Antibody (Preservative Free) LS-C814945

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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NR0B1 / DAX1 Antibody (clone 2F12) LS-C196629

Antibody:

NR0B1 / DAX1 Mouse anti-Human Monoclonal (2F12) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$423

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NR0B1 / DAX1 Antibody LS-C768621

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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NR0B1 / DAX1 Antibody LS-C192687

Antibody:

NR0B1 / DAX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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NR0B1 / DAX1 Antibody (aa161-430, clone OTI5F5) LS-C339430

Antibody:

NR0B1 / DAX1 Mouse anti-Human Monoclonal (aa161-430) (OTI5F5) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$434

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NR0B1 / DAX1 Antibody (aa161-430, clone OTI5F5, Carrier-free) LS-C790479

Antibody:

NR0B1 / DAX1 Mouse anti-Human Monoclonal (aa161-430) (Carrier-free) (OTI5F5) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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