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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1075-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human NPY5R Antibody (Cytoplasmic Domain, IHC) LS‑A1075
PathPlus™ Polyclonal Rabbit anti‑Human NPY5R Antibody (Cytoplasmic Domain, IHC) LS‑A1075
Antibody:
NPY5R Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
NPY5R Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
NPY5R (Neuropeptide Y receptor type 5) is a receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. It is associated with food intake and could be involved in feeding disorders. In neuroblastoma, copy-number alterations in NPY5R have been observed, and it is overexpressed specifically in chemotherapy-treated tumors and is thought to be involved in a chemoresistant pro-survival loop.
References: Can Res Tumor Biology. 2017. 77 (13). DOI: 10.1158/1538-7445.AM2017-5822; Oncogene. 2015 Jun 11;34(24):3131-43, PMID: 25132261
Target
Human NPY5R
Synonyms
NPY5R | NPYR5 | NPY5-R | NPYY5 | Neuropeptide Y receptor Y5 | NPYY5-R | Neuropeptide Y receptor type 5 | Neuropeptide Y5 receptor | NPY-Y5 receptor | NPY5 receptor | Y5 receptor
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Dog, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human NPY5R. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Mouse, Rat, Bovine, Dog, Hamster, Panda (94%); Rabbit, Pig (88%).
Epitope
Cytoplasmic Domain
Specificity
Human NPY5R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (16 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Failed Applications
- ICC
- Western blot
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NPY5R
Validation
Breast, carcinoma
Breast, carcinoma
Colon, Carcinoma
Colon, Carcinoma
Lung, Non Small-Cell Carcinoma
Lung, Non Small-Cell Carcinoma
Anti-NPY5R antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPY5R antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ NPY5R Antibody (Cytoplasmic Domain) for IHC LS-A1075 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Reactivity:
All species
Range:
123.5-10000 pg/ml
Reactivity:
Human
Range:
0.156-10 ng/ml
Source:
E. coli
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
