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NKX2-1 / Thyroid-Specific TF
NK2 homeobox 1
TTF-1 / Thyroid-Specific TF is a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
| Gene Name: | NK2 homeobox 1 |
| Synonyms: | NKX2-1, BCH, Benign chorea, Homeobox protein Nkx-2.1, NK-2, NKX2.1, NK-2 homolog A, Thyroid transcription factor 1, NK2 homeobox 1, TTF-1, BHC, Thyroid nuclear factor 1, TITF1, NKX2A, TEBP |
| Target Sequences: | NM_003317 NP_003308.1 P43699 |
Publications (2)
1
Dorsal radial glial cells have the potential to generate cortical interneurons in human but not in mouse brain. Yu X, Zecevic N. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 31:2413-20. (IHC)
[PubMed:21325508]
[PMC:PMC3079257]
2
Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation. Sandra L Leibel, Rachael N McVicar, Alicia M Winquist, Walter D Niles, Evan Y Snyder. Current protocols in stem cell biology. 2020 September;54:e118. [Full Text Article]
[PubMed:32640120]
[PMC:PMC7361156]
Related Antibodies: LS-C264437.
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NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$460
![NKX2-1 / Thyroid-Specific TF Antibody - Immunofluorescence of monoclonal antibody to NKX2-1 on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/nkx2-1-thyroid-specific-tf-antibody-clone-2b9-ls-c198345/146791_4983173.jpg)
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (2B9) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Azide-free, BSA-free) (NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Ready-to-Use) (NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (8G7G3/1 + NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Ready-to-Use) (8G7G3/1 + NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Azide-free, BSA-free) (8G7G3/1 + NX2.1/690) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Rat Monoclonal Antibody
Rat, Human
ICC, IF, IHC, IHC-Fr, IHC-P
Unconjugated
1 ml/$952
NKX2-1 / Thyroid-Specific TF Mouse anti-Rat Monoclonal (8G7G3/1) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Rat Monoclonal (Azide-free, BSA-free) (8G7G3/1) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Carrier-free) (OTI10F8) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (OTI10F8) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$434
Cancer Pathology
Cancer
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Recombinant Monoclonal (rNX2.1/690) Antibody
Human
IHC-P
Unconjugated
100 µg/$525
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Carrier-free) (OTI3F3) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (OTI3D7) Antibody
Human
Flo, IF
Unconjugated
100 µl/$434
NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (OTI3E2) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (Concentrated) (8G7G3/1) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
1 ml/$588
NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
200 µl/$801
NKX2-1 / Thyroid-Specific TF Rabbit anti-Human Polyclonal Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
NKX2-1 / Thyroid-Specific TF Mouse anti-Human Monoclonal (OTI1C5) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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