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NFATC1 / NFAT2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Gene Name: nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Synonyms: NFATC1, NFATc, NFAT2, NF-ATC, NF-ATC transcription factor, NF-ATc1
Target Sequences: NM_006162 NP_006153.2 O95644

Publications (1)

1
Isolation and Characterization of Multipotent CD24+ Cells From the Renal Papilla of Swine. Burmeister DM, McIntyre MK, Montgomery RK, Gómez BI, Dubick MA. Frontiers in medicine. 2018 September;5:250. [Full Text Article] [PubMed:30283781] [PMC:PMC6156461]

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Antibodies (68)
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NFATC1 / NFAT2 (82)
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NFATC1 / NFAT2 Antibody - Anti-NFATC1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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NFATC1 / NFAT2 Mouse anti-Human Monoclonal (aa428-716) (AT1C3) Antibody
Human
ELISA, IF, IHC, IHC-P, SDS-PAGE, WB
Unconjugated
50 µl/$460
NFATC1 / NFAT2 Antibody - Immunohistochemistry of paraffin-embedded human esophageal cancer using NFATC1 antibody at dilution of 1:200 (x400 lens).
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
NFATC1 / NFAT2 Antibody - Anti-NFATC1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa263-282) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
NFATC1 / NFAT2 Antibody - NFATC1 antibody Western blot of COLO205 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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NFATC1 / NFAT2 Mouse anti-Human Monoclonal (aa1-654) Antibody
Mouse, Human
Flo, GS, ICC, IP, WB
Unconjugated
100 µl/$1,027
NFATC1 / NFAT2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
NFATC1 / NFAT2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$923
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (pSer294) Antibody
Mouse, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
NFATC1 / NFAT2 Antibody - Western blot - Anti-NFAT2 Picoband Antibody
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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NFATC1 / NFAT2 Mouse anti-Human Monoclonal (pSer172) (TS106) Antibody
Human
WB
Unconjugated
100 µg/$941
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NFATC1 / NFAT2 Goat anti-Human Polyclonal (aa48-406) Antibody
Human
WB
Unconjugated
100 µg/$929
NFATC1 / NFAT2 Antibody - Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution of 1:100
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal Antibody
Human
ChrIP, GS, ICC, IHC, IP, WB
Unconjugated
50 µg/$505
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NFATC1 / NFAT2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
NFATC1 / NFAT2 Antibody - Immunohistochemistry of NFATc1 antibody
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (881-930 aa, C-terminal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NFATC1 / NFAT2 Antibody - NFATC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (aa898-927) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
NFATC1 / NFAT2 Antibody - 1:100 staining human liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NFATC1 / NFAT2 Rabbit anti-Human Polyclonal (230-310 aa) Antibody
Mouse, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 82 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).