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Myosin VI / MYO6

Myosin VI

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells.

Gene Name: Myosin VI
Synonyms: MYO6, DFNB37, DFNA22, Myosin VI, Myosin-VI, Unconventional myosin-VI, Unconventional myosin-6, KIAA0389
Target Sequences: AL136093 CAI42823.1 Q9UM54

☰ Filters
Antibodies (17)
Proteins (2)
Primary (17)
Recombinant (2)
Myosin VI / MYO6 (19)
Human (17)
Mouse (6)
Rat (5)
Chicken (1)
Pig (3)
IHC (10)
IHC-P (2)
WB (17)
ELISA (11)
ICC (5)
IF (8)
IP (1)
Peptide-ELISA (1)
rabbit (16)
mouse (1)
Product Group
IHCPlus (1)
IgG (11)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (16)
2E12 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (12)
aa1166-1195 (7)
40-120 aa, N-terminal (1)
N-Terminus (1)
No (19)
GST, N-terminus (1)
Myc-DDK (Flag) (1)
Human (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Myosin VI / MYO6 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Rat, Pig, Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Myosin VI / MYO6 Antibody - MYO6 Antibody (C-term R1181) immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IP, WB
Unconjugated
200 µl/$468
Myosin VI / MYO6 Antibody - Western blot analysis of extracts of various cell lines, using MYO6 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
Select
Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) (Biotin) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) (Azide-free) (HRP) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (aa1166-1195) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Myosin VI / MYO6 Antibody - Immunofluorescence analysis of HeLa cells using MYO6 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Myosin VI / MYO6 Antibody - 1:100 staining mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Myosin VI / MYO6 Antibody - MYO6 monoclonal antibody (M02), clone 2E12. Western Blot analysis of MYO6 expression in MCF-7.
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Myosin VI / MYO6 Mouse anti-Human Monoclonal (2E12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Myosin VI / MYO6 Antibody - Western blot of Myosin VI antibody
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal (40-120 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Myosin VI / MYO6 Antibody - Western Blot of Rabbit anti-Myosin-6 antibody. Lane 1: SF9 cell lysate of truncated smooth myosin. Lane 2: Jurkat lysate. Lane 3: LnCap lysate. Lane 4: Recombinant myosin VI Load: 35 ug per lane for cell lysate. 50 ng of recombinant protein. Primary antibody: Myosin 6 antibody at 1:1000 for overnight at 4 degrees C. Secondary antibody: HRP rabbit secondary antibody at 1:40,000 for 60 min at RT. Block: 5% BLOTTO overnight at 4 degrees C. Predicted/Observed size: 150 kDa for Myo6.
Select
Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Pig, Human
ELISA, WB
Unconjugated
100 µl/$567
Myosin VI / MYO6 Antibody - Western Blot of rabbit anti-Myosin-6 antibody. Lane 1: SF9 cell lysate of truncated smooth myosin. Lane 2: Jurkat lysate. Lane 3: LnCap lysate. Lane 4: Recombinant myosin VI Load: 20µg per lane for cell lysate. 50ng of recombinant protein. Primary antibody: Myosin 6 antibody at 1:1000 for overnight at 4°C. Secondary antibody: HRP rabbit secondary antibody at 1:40,000 for 60 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 150 kDa for Myo6.
Select
Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Pig, Human
ELISA, WB
Unconjugated
25 µl/$304
Myosin VI / MYO6 Antibody - Immunohistochemical analysis of paraffin-embedded Human-heart, antibody was diluted at 1:100.
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Myosin VI / MYO6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Myosin VI / MYO6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Myosin VI / MYO6 Protein - Purified recombinant protein MYO6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
148.5 kDa
20 µg/$1,107
Viewing 1-19 of 19 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).