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MURF1 / IRF

tripartite motif containing 63, E3 ubiquitin protein ligase

E3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.

Gene Name: tripartite motif containing 63, E3 ubiquitin protein ligase
Family/Subfamily: Tripartite Motif
Synonyms: TRIM63, Iris RING finger protein, MURF-1, MURF1, MuRF2, IRF, RING finger protein 28, RNF28, Tripartite motif-containing 63, Tripartite motif containing 63, SMRZ
Target Sequences: NM_032588 NP_115977.2 Q969Q1

☰ Filters
Antibodies (21)
ELISA Kits (6)
Proteins (4)
Custom (2)
Over-Expression Lysate (2)
Primary (21)
Recombinant (2)
Sandwich (4)
MURF1 / IRF (31)
Human (23)
Mouse (14)
Rat (6)
Bat (3)
Bovine (8)
Chimpanzee (6)
Dog (4)
Gibbon (3)
Guinea pig (6)
Horse (4)
Monkey (5)
Pig (4)
Rabbit (3)
IHC (10)
IHC-P (3)
WB (17)
Flo (1)
ELISA (6)
ICC (2)
IF (6)
Peptide-ELISA (3)
rabbit (17)
mouse (2)
goat (2)
Product Group
IHCPlus (2)
IgG (6)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (19)
6H6D4 (1)
7B8E1 (1)
96-Well Microplate (1)
96-Well Strip Plate (5)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (15)
aa186-235 (4)
aa251-300 (4)
aa1-44 (1)
aa2-14 (1)
aa247-261 (1)
No (31)
Cell Lysates (2)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
MURF1 / IRF Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using TRIM63 Polyclonal Antibody at dilution of 1:70.
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MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MURF1 / IRF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$768
MURF1 / IRF Antibody - Anti-TRIM63 / MURF1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 25 ug/ml.
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MURF1 / IRF Goat anti-Human Polyclonal (aa247-261) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
MURF1 / IRF Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MURF1 / IRF Antibody - TRIM63 / MURF1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
WB
Unconjugated
100 µl/$424
MURF1 / IRF Antibody - TRIM63 / MURF1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
MURF1 / IRF Antibody - TRIM63 / MURF1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa251-300) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
MURF1 / IRF Antibody - TRIM63 / MURF1 antibody Western blot of THP-1 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa251-300) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
MURF1 / IRF Antibody - Anti-TRIM63 / MURF1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 25 ug/ml.
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MURF1 / IRF Goat anti-Human Polyclonal (aa2-14) Antibody
Dog, Bovine, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
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MURF1 / IRF Mouse anti-Human Monoclonal (7B8E1) Antibody
Human
ELISA, Flo, IF, IHC
Unconjugated
100 µl/$459
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MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
MURF1 / IRF Antibody - IHC of paraffin-embedded Breast ca using MURF1 antibody at 1:500 dilution.
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa1-44) Antibody
Bovine, Pig, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$402
MURF1 / IRF Antibody - Immunohistochemistry of paraffin-embedded human esophagus cancer tissue.
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MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
MURF1 / IRF ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Select
MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
MURF1 / IRF Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using TRIM63 Polyclonal Antibody at dilution of 1:60.
Select
MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
MURF1 / IRF Mouse anti-Human Monoclonal (6H6D4) Antibody
Human
ELISA, IHC
Unconjugated
100 µl/$459
Select
MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
MURF1 / IRF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
MURF1 / IRF Rabbit anti-Human Polyclonal (aa186-235) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
MURF1 / IRF Rabbit anti-Human Polyclonal (aa186-235) (HRP) Antibody
Mouse, Guinea pig, Bovine, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa186-235) (Biotin) Antibody
Mouse, Guinea pig, Bovine, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
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MURF1 / IRF Rabbit anti-Human Polyclonal (aa186-235) (FITC) Antibody
Mouse, Guinea pig, Bovine, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
MURF1 / IRF Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MURF1 / IRF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.1 kDa
100 µg/$494
Viewing 1-25 of 31 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).