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| Catalog Number | Size | Price |
|---|---|---|
| LS-A934-50 | 50 µg (0.7 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human MTNR1B / MT2 Antibody (Extracellular Domain, IHC) LS‑A934
PathPlus™ Polyclonal Rabbit anti‑Human MTNR1B / MT2 Antibody (Extracellular Domain, IHC) LS‑A934
Antibody:
MTNR1B / MT2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
MTNR1B / MT2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
Melatonin receptor 1B (MTNR1B) is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. MTNR1B is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human MTNR1B / MT2
Synonyms
MTNR1B | MEL-1B-R | Mel-1b melatonin receptor | Melatonin receptor 1B | Melatonin receptor MEL1B | Mt2r | MT2 melatonin receptor | MtT2 receptor | Melatonin receptor type 1B | MT2 | FGQTL2 | Mel1b receptor
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 3rd extracellular domain of human MTNR1B. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Elephant, Bat, Horse (88%); Rat (81%).
Epitope
Extracellular Domain
Specificity
Human MTNR1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (5 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MTNR1B / MT2
Validation
Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Eye, Retina
Eye, Retina
Brain, Pituitary
Brain, Pituitary
Anti-MTNR1B / MT2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MTNR1B / MT2 antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ MTNR1B / MT2 Antibody (Extracellular Domain) for IHC LS-A934 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Rat
Applications:
Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
