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MTNR1B / MT2

melatonin receptor 1B

MTNR1B / MT2 is one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.

Gene Name: melatonin receptor 1B
Family/Subfamily: GPCR , Melatonin
Synonyms: MTNR1B, MEL-1B-R, Mel-1b melatonin receptor, Melatonin receptor 1B, Melatonin receptor MEL1B, Mt2r, MT2 melatonin receptor, MtT2 receptor, Melatonin receptor type 1B, MT2, FGQTL2, Mel1b receptor
Target Sequences: NM_005959 NP_005950.1 P49286

Publications (1)

1
Urinary Melatonin in Relation to Postmenopausal Breast Cancer Risk According to Melatonin 1 Receptor Status. Devore EE, Warner ET, Eliassen AH, Brown SB, Beck AH, Hankinson SE, Schernhammer ES. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2017 March;26:413-419. (Human) [Full Text Article] [PubMed:28151704] [PMC:PMC5336486] Related Antibodies: LS-A930.

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Antibodies (22)
ELISA Kits (5)
Primary (22)
Sandwich (4)
Sandwich CLIA (1)
MTNR1B / MT2 (27)
Human (24)
Rat (1)
Chicken (1)
Chimpanzee (3)
Monkey (2)
Sheep (1)
IHC (7)
IHC-P (5)
WB (12)
ELISA (9)
IF (2)
Peptide-ELISA (4)
rabbit (21)
goat (1)
Product Group
GPCR Database Antibodies (4)
IHCPlus (3)
PathPlus Neuro (2)
IgG (10)
polyclonal pc (22)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (4)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (16)
N-Terminus (5)
C-Terminus (2)
270-350 aa, C-terminal (1)
Cytoplasmic Domain (1)
Extracellular Domain (1)
Val39 (1)
aa301-350 (1)
aa334-348 (1)
aa39-88 (1)
No (26)
Yes (1)
Cell Lysates (1)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
MTNR1B / MT2 Antibody - Anti-MTNR1B / MT2 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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MTNR1B / MT2 Goat anti-Human Polyclonal (aa334-348) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
MTNR1B / MT2 Antibody - Anti-MTNR1B antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
MTNR1B / MT2 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MTNR1B / MT2 Antibody - Immunohistochemistry of paraffin-embedded human eye tissue using MTNR1B Antibody at dilution of 1:100
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MTNR1B / MT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
MTNR1B / MT2 Antibody - Immunohistochemistry of paraffin-embedded Human brain tissue  using MTNR1B Polyclonal Antibody at dilution of 1:55(×200)
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MTNR1B / MT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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MTNR1B / MT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
MTNR1B / MT2 Antibody - Western blot of MEL-1B-R antibody
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (270-350 aa, C-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MTNR1B / MT2 Antibody - Western blot analysis of lysates from 293, Jurkat, and HepG2 cells, using MTR1B Antibody. The lane on the right is blocked with the synthesized peptide.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MTNR1B / MT2 Antibody - Western blot analysis of the lysates from HeLa cells using MTR1B antibody.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (aa39-88) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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MTNR1B / MT2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$386
MTNR1B / MT2 Antibody - MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
MTNR1B / MT2 Antibody - MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
MTNR1B / MT2 Antibody - MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
MTNR1B / MT2 Antibody - MTNR1B / MT2 antibody Western Blot of HepG2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
MTNR1B / MT2 Antibody - Western blot analysis of Melatonin Receptor 1b expression in A549 (A); HeLa (B); HEK293T (C) whole cell lysates.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
MTNR1B / MT2 Antibody - Western blot of MEL-1B-R (V39) pAb in extracts from 293/Jurkat/HepG2 cells.
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MTNR1B / MT2 Rabbit anti-Human Polyclonal (Val39) Antibody
Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
MTNR1B / MT2 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MTNR1B / MT2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MTNR1B / MT2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).